F-actin-uncapping protein LRRC16A (CARMIL1) Antibody
Pida mas información
935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-CARMIL1
proveedor
Abbexareference
abx346417Tested Applications
ELISA, IF/ICCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
F-actin-uncapping protein LRRC16A (CARMIL1) Antibody is a Rabbit Polyclonal antibody for the detection of Human CARMIL1.
Background
CARMIL1 is a scaffolding protein that regulates actin dynamics by interacting with capping proteins, the Arp2/3 complex, and myosin-I. It plays a critical role in actin filament assembly and disassembly, essential for cell migration, adhesion, and membrane trafficking. CARMIL1 is required for proper lamellipodia and filopodia formation, contributing to cell shape and motility. Dysregulation of CARMIL1 has been linked to cancer metastasis and immune dysfunction, where altered actin remodeling affects cell invasion and signaling. It also participates in signaling pathways related to integrins and cytoskeletal reorganization, making it a target for therapeutic research in metastatic cancer and immune disorders.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
F-actin-uncapping protein LRRC16A (CARMIL1)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, IF/ICC
purity
> 95%
purification
Purified by Protein G chromatography.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CARMIL1
dry ice
No
availability
Shipped within 5-10 working days.
alias
F-actin-uncapping protein LRRC16A,CARMIL1,CARMIL,Leucine-rich repeat-containing protein 16A
uniprot id
note
This product is for research use only.
Quizá le pueda interesar
Leucine-Rich Repeat-Containing Protein 16A (LRRC16A) Antibody
proveedor
Abbexareference
abx030121Tested Applications
ELISA, WBreactivity
Human, Mousestatus
RUOclonality
PolyclonalLRRC16A binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the...
250€ (80 µl)
Ver másF-actin-uncapping protein LRRC16A (CARMIL1) Antibody
proveedor
Abbexareference
abx346417Tested Applications
ELISA, IF/ICCreactivity
Humanstatus
RUOclonality
PolyclonalF-actin-uncapping protein LRRC16A (CARMIL1) Antibody is a Rabbit Polyclonal antibody for the detection of Human CARMIL1....
162.5€ (20 µg)
Ver másF-actin-uncapping protein LRRC16A (CARMIL1) Antibody (HRP)
proveedor
Abbexareference
abx346418Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalF-actin-uncapping protein LRRC16A (CARMIL1) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the det...
162.5€ (20 µg)
Ver más