F-actin-uncapping protein LRRC16A (CARMIL1) Antibody (FITC)
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935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-CARMIL1
proveedor
Abbexareference
abx346419Tested Applications
reactivity
Humanstatus
RUOclonality
PolyclonalDescripción
F-actin-uncapping protein LRRC16A (CARMIL1) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human CARMIL1.
Background
CARMIL1 is a scaffolding protein that regulates actin dynamics by interacting with capping proteins, the Arp2/3 complex, and myosin-I. It plays a critical role in actin filament assembly and disassembly, essential for cell migration, adhesion, and membrane trafficking. CARMIL1 is required for proper lamellipodia and filopodia formation, contributing to cell shape and motility. Dysregulation of CARMIL1 has been linked to cancer metastasis and immune dysfunction, where altered actin remodeling affects cell invasion and signaling. It also participates in signaling pathways related to integrins and cytoskeletal reorganization, making it a target for therapeutic research in metastatic cancer and immune disorders.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
F-actin-uncapping protein LRRC16A (CARMIL1)
host
Rabbit
conjugation
FITC
form
Liquid
purity
> 95%
purification
Purified by Protein G chromatography.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CARMIL1
dry ice
No
availability
Shipped within 5-10 working days.
alias
F-actin-uncapping protein LRRC16A,CARMIL1,CARMIL,Leucine-rich repeat-containing protein 16A
uniprot id
note
This product is for research use only.
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