Coronin-2A (CORO2A) Antibody
357.5€ (100 µg)
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Name
Coronin-2A (CORO2A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx145379
Tested Applications
ELISA, WB, IHC
Description
CORO2A Antibody is a Rabbit Polyclonal against CORO2A.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Coronin-2A (CORO2A) Immunogen: Recombinant fragment corresponding to 26-204 AA of human CORO2A. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 20 kDa (Recombinant Protein) |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC000010 |
| Alias | IR10,WDR2,CLIPINB,WD repeat-containing protein 2,Coronin-2A |
| Background | Antibody anti-CORO2A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Coronin 2A (CORO2A) is part of the coronin protein family, and it plays a key role in regulating actin dynamics and cell movement. Similar to other coronin proteins, CORO2A is involved in cellular processes like endocytosis, cytokinesis, and cell migration. Its function is particularly important in immune cells and neurons, where it helps coordinate the movement and function of these cells during immune responses and synaptic activity. CORO2A has been implicated in the regulation of immune cell signaling, particularly in T cells, where it aids in cell motility and immune synapse formation. This makes CORO2A an essential protein for both immune responses and neuronal processes. Dysregulation or mutations in CORO2A have been linked to immune-related diseases and could impact the efficacy of the immune system’s response to pathogens.
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