Coronin-2A (CORO2A) Antibody

Name: Coronin-2A (CORO2A) Antibody
Brand: Abbexa
SKU: abx027487
Price: 250 EUR
Availability: OnlineOnly

Este producto es parte de CORO - Coronin

Pida mas información

935106861

info@markelab.com

Precio

250€ (80 µl)

Antibody anti-CORO2A

proveedor

Abbexa

reference

abx027487

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.

Background

Coronin 2A (CORO2A) is part of the coronin protein family, and it plays a key role in regulating actin dynamics and cell movement. Similar to other coronin proteins, CORO2A is involved in cellular processes like endocytosis, cytokinesis, and cell migration. Its function is particularly important in immune cells and neurons, where it helps coordinate the movement and function of these cells during immune responses and synaptic activity. CORO2A has been implicated in the regulation of immune cell signaling, particularly in T cells, where it aids in cell motility and immune synapse formation. This makes CORO2A an essential protein for both immune responses and neuronal processes. Dysregulation or mutations in CORO2A have been linked to immune-related diseases and could impact the efficacy of the immune system’s response to pathogens.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Coronin-2A (CORO2A)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purification

Purified through a protein A column, followed by peptide affinity purification.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

CORO2A

dry ice

availability

Shipped within 5-10 working days.

alias

IR10,WDR2,CLIPINB,WD repeat-containing protein 2,Coronin-2A

uniprot id

https://www.uniprot.org/uniprotkb/Q92828

note

This product is for research use only.

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