Family main features
AKT2, also known as RAC-beta serine/threonine-protein kinase, is one of the three isoforms of the AKT (Protein Kinase B) family of serine/threonine kinases. Like other AKT isoforms, AKT2 plays a crucial role in various cellular processes, including metabolism, cell survival, proliferation, and growth. AKT2 is a downstream effector of the PI3K (phosphoinositide 3-kinase) signaling pathway. Activation of AKT2 occurs through phosphorylation at key residues, including threonine 309 (Thr309) and serine 474 (Ser474). Once activated, AKT2 phosphorylates a wide range of substrates involved in diverse cellular functions. AKT2 regulates glucose uptake by promoting the translocation of glucose transporter type 4 (GLUT4) to the cell membrane, thereby facilitating glucose uptake into cells, particularly in insulin-responsive tissues like muscle and adipose tissue. Dysregulation of AKT2 signaling has been implicated in insulin resistance and type 2 diabetes. AKT2 is also involved in other cellular processes such as cell proliferation, survival, and migration. Dysregulation of AKT2 signaling has been implicated in various diseases, including cancer, metabolic disorders, and cardiovascular diseases.
Clinical Issues:
AKT2 is a critical kinase in the AKT family, predominantly involved in regulating glucose metabolism and insulin signaling. Its activation and functions are crucial for normal cellular metabolism, growth, and survival. Dysregulation of AKT2 is implicated in various pathologies, including cancer and metabolic disorders, making it a significant target for therapeutic interventions. Understanding the specific roles and regulatory mechanisms of AKT2 provides valuable insights into its contribution to health and disease.
RAC-beta serine/threonine-protein kinase (AKT2)
AKT2,PKB beta,Protein kinase Akt ,Protein kinase B beta
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits, CLIA Kits) relacionados con AKT2 - RAC-beta serine/threonine-protein kinase 2
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Esta página contiene 37 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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FineTest | AKT2 | EH15498 | Human AKT2(RAC-beta serine/threonine-protein kinase) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | P31751 | RUO | ||
Abbexa | AKT2 | abx253501 | Human RAC-Beta Serine/Threonine-Protein Kinase (AKT2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | < 27 pg/ml | 662.5 | 96 tests | P31751 | RUO |
Abbexa | AKT2 | abx493020 | Human RAC-Beta Serine/Threonine-Protein Kinase (AKT2) CLIA Kit | Human | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.124 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | AKT2 | abx152856 | Human RAC-Beta Serine/Threonine-Protein Kinase (AKT2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | < 30 pg/ml | 662.5 | 96 tests | RUO | |
Abbexa | AKT2 | abx595025 | RAC-Beta Serine/Threonine-Protein Kinase (AKT2) Cell ELISA Kit | Human | Cell ELISA | 493.75 | 96 tests | P31751 | RUO | |||
Abbexa | AKT2 | abx576742 | Mouse RAC-Beta Serine/Threonine-Protein Kinase (AKT2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q60823 | RUO | |
FineTest | Akt2 | ER0703 | Rat Akt2(RAC-beta serine/threonine-protein kinase) ELISA Kit | rat | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 15.625-1000pg/ml | 96T | P47197 | RUO | ||
Abbexa | AKT2 | abx493021 | Rat RAC-Beta Serine/Threonine-Protein Kinase (AKT2) CLIA Kit | Rat | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.114 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | AKT2 | abx156016 | Rat RAC-Beta Serine/Threonine-Protein Kinase (AKT2) ELISA Kit | Rat | Tissue homogenates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.12 ng/ml | 687.5 | 96 tests | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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FineTest | AKT2 | FNab00272 | anti- AKT2 antibody | human | polyclonal | Rabbit | v-akt murine thymoma viral oncogene homolog 2 | IgG | Unconjugated | ELISA, WB, IHC, IP | 100µg | P31751 | RUO | |
Abbexa | AKT2 | abx033127 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IHC, IF/ICC, FCM | 250 | 80 µl | P31751 | RUO | |
Abbexa | AKT2 | abx031949 | RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) | Unconjugated | ELISA, DB | 281.25 | 80 µl | P31751 | RUO | |
Abbexa | AKT2 | abx033129 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IHC, IF/ICC | 250 | 80 µl | P31751 | RUO | |
Abbexa | AKT2 | abx107275 | RAC-beta serine/threonine-protein kinase (AKT2) Antibody (FITC) | Human | Polyclonal | Rabbit | RAC-beta serine/threonine-protein kinase (AKT2) | FITC | 162.5 | 20 µg | P31751 | RUO | ||
Abbexa | AKT2 | abx432304 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Goat | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | P-ELISA, WB | 387.5 | 200 µl | RUO | ||
Abbexa | AKT2 | abx037427 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | AKT2 | abx108695 | RAC-beta serine/threonine-protein kinase (AKT2) Antibody (HRP) | Human | Polyclonal | Rabbit | RAC-beta serine/threonine-protein kinase (AKT2) | HRP | ELISA | 162.5 | 20 µg | P31751 | RUO | |
Abbexa | AKT2 | abx037428 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | AKT2 | abx105859 | RAC-beta serine/threonine-protein kinase (AKT2) Antibody (Biotin) | Human | Polyclonal | Rabbit | RAC-beta serine/threonine-protein kinase (AKT2) | Biotin | ELISA | 162.5 | 20 µg | P31751 | RUO | |
Abbexa | AKT2 | abx033128 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IHC, IF/ICC, FCM | 250 | 80 µl | P31751 | RUO | |
Abbexa | AKT2 | abx027682 | RAC-Beta Serine/threonine-Protein Kinase (Akt2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (Akt2) | Unconjugated | ELISA, WB, IHC | 281.25 | 80 µl | Q60823 | RUO | |
Abbexa | AKT2 | abx033130 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IF/ICC, FCM | 250 | 80 µl | P31751 | RUO | |
Abbexa | AKT2 | abx000688 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | WB, IF/ICC | 175 | 20 µl | P31751 | RUO | |
Abbexa | AKT2 | abx329152 | RAC-beta serine/threonine-protein kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-beta serine/threonine-protein kinase (AKT2) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | P31751 | RUO | |
Abbexa | AKT2 | abx119265 | RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) | Unconjugated | WB, IHC | 43.75 | 10 µg | P31751 | RUO | |
Abbexa | AKT2 | abx328438 | RAC-beta serine/threonine-protein kinase Phospho-Ser474 (AKT2 pS474) Antibody | Human | Polyclonal | Rabbit | RAC-beta serine/threonine-protein kinase Phospho-Ser474 (AKT2 pS474) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | P31751 | RUO | |
Abbexa | AKT2 | abx000095 | RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) | Unconjugated | WB | 200 | 20 µl | P31751 | RUO | |
Abbexa | AKT2 | abx214896 | RAC-beta serine/threonine-protein kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-beta serine/threonine-protein kinase (AKT2) | Unconjugated | ELISA, IHC | 250 | 50 µl | P31751 | RUO | |
Abbexa | AKT2 | abx214925 | RAC-beta serine/threonine-protein kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-beta serine/threonine-protein kinase (AKT2) | Unconjugated | ELISA, IHC | 250 | 50 µl | P31751 | RUO | |
Abbexa | AKT2 | abx230272 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IHC, IP | 350 | 100 µg | P31751 | RUO | |
Abbexa | AKT2 | abx117081 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IHC | 450 | 100 µl | P31751 | RUO | |
Abbexa | AKT2 | abx333258 | RAC-beta serine/threonine-protein kinase Phospho-Ser474 (AKT2 pS474) Antibody | Human | Polyclonal | Rabbit | RAC-beta serine/threonine-protein kinase Phospho-Ser474 (AKT2 pS474) | Unconjugated | ELISA, WB, IHC | 412.5 | 100 µl | P31751 | RUO | |
Abbexa | AKT2 | abx329766 | RAC-beta serine/threonine-protein kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-beta serine/threonine-protein kinase (AKT2) | Unconjugated | WB, IHC | 187.5 | 50 µg | P31751 | RUO | |
Abbexa | AKT2 | abx025205 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Monoclonal | Mouse | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IHC, IF/ICC | 281.25 | 80 µl | P31751 | RUO | |
Abbexa | AKT2 | abx109362 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Polyclonal | Rabbit | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | P31751 | RUO | |
Abbexa | AKT2 | abx010368 | RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody | Human | Monoclonal | Mouse | RAC-Beta Serine/threonine-Protein Kinase (AKT2) | Unconjugated | ELISA, WB, IHC, IF/ICC | 362.5 | 100 µl | P31751 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | AKT2 | P0509 | Recombinant Human AKT2 | Human | Recombinant | E.Coli | Western Blot, ELISA | 50μg | P31751 | RUO |
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