RAC-beta serine/threonine-protein kinase (AKT2) Antibody
Pida mas información
935106861
info@markelab.com
Precio
250€ (50 µl)
Antibody anti-AKT2
proveedor
Abbexareference
abx214925Tested Applications
ELISA, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
AKT2 Antibody is a Rabbit Polyclonal against AKT2.
Background
AKT2, also known as RAC-beta serine/threonine-protein kinase, is one of the three isoforms of the AKT (Protein Kinase B) family of serine/threonine kinases. Like other AKT isoforms, AKT2 plays a crucial role in various cellular processes, including metabolism, cell survival, proliferation, and growth. AKT2 is a downstream effector of the PI3K (phosphoinositide 3-kinase) signaling pathway. Activation of AKT2 occurs through phosphorylation at key residues, including threonine 309 (Thr309) and serine 474 (Ser474). Once activated, AKT2 phosphorylates a wide range of substrates involved in diverse cellular functions. AKT2 regulates glucose uptake by promoting the translocation of glucose transporter type 4 (GLUT4) to the cell membrane, thereby facilitating glucose uptake into cells, particularly in insulin-responsive tissues like muscle and adipose tissue. Dysregulation of AKT2 signaling has been implicated in insulin resistance and type 2 diabetes. AKT2 is also involved in other cellular processes such as cell proliferation, survival, and migration. Dysregulation of AKT2 signaling has been implicated in various diseases, including cancer, metabolic disorders, and cardiovascular diseases.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
RAC-beta serine/threonine-protein kinase (AKT2)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, IHC
purification
Antigen Affinity Chromatography.
buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
size 1
50 µl
size 2
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
AKT2
dry ice
No
availability
Shipped within 5-10 working days.
alias
AKT2,PKB beta,Protein kinase Akt ,Protein kinase B beta
uniprot id
note
This product is for research use only.
Quizá le pueda interesar
Human AKT2(RAC-beta serine/threonine-protein kinase) ELISA Kit
proveedor
FineTestreference
EH15498reactivity
humanstatus
RUOPrecio a consultar
Ver másanti- AKT2 antibody
proveedor
FineTestreference
FNab00272Tested Applications
ELISA, WB, IHC, IPreactivity
human,mouse,ratstatus
RUOclonality
polyclonalAKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which...
Precio a consultar
Ver másRecombinant Human AKT2
proveedor
FineTestreference
P0509Tested Applications
Western Blot, ELISAstatus
RUOPrecio a consultar
Ver más