RAC-beta serine/threonine-protein kinase (AKT2) Antibody

Este producto es parte de AKT2 - RAC-beta serine/threonine-protein kinase 2
RAC-beta serine/threonine-protein kinase (AKT2) Antibody

Pida mas información

935106861

info@markelab.com

Precio

250€ (50 µl)

Antibody anti-AKT2

proveedor

Abbexa

reference

abx214925

Tested Applications

ELISA, IHC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

AKT2 Antibody is a Rabbit Polyclonal against AKT2.


Background

AKT2, also known as RAC-beta serine/threonine-protein kinase, is one of the three isoforms of the AKT (Protein Kinase B) family of serine/threonine kinases. Like other AKT isoforms, AKT2 plays a crucial role in various cellular processes, including metabolism, cell survival, proliferation, and growth. AKT2 is a downstream effector of the PI3K (phosphoinositide 3-kinase) signaling pathway. Activation of AKT2 occurs through phosphorylation at key residues, including threonine 309 (Thr309) and serine 474 (Ser474). Once activated, AKT2 phosphorylates a wide range of substrates involved in diverse cellular functions. AKT2 regulates glucose uptake by promoting the translocation of glucose transporter type 4 (GLUT4) to the cell membrane, thereby facilitating glucose uptake into cells, particularly in insulin-responsive tissues like muscle and adipose tissue. Dysregulation of AKT2 signaling has been implicated in insulin resistance and type 2 diabetes. AKT2 is also involved in other cellular processes such as cell proliferation, survival, and migration. Dysregulation of AKT2 signaling has been implicated in various diseases, including cancer, metabolic disorders, and cardiovascular diseases.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Mouse, Rat


immunogen target

RAC-beta serine/threonine-protein kinase (AKT2)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, IHC


purification

Antigen Affinity Chromatography.


buffer

PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.


size 1

50 µl


size 2

100 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

AKT2


dry ice

No


availability

Shipped within 5-10 working days.


alias

AKT2,PKB beta,Protein kinase Akt ,Protein kinase B beta


note

This product is for research use only.


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