Family main features
NCKAP (NCK-associated protein) is a critical component of the WAVE (WASP family Verprolin-homologous protein) complex involved in the regulation of the actin cytoskeleton. This protein is vital for various cellular processes, including cell motility, adhesion, and signaling. NCKAP, through its role in the WAVE complex, links extracellular signals to actin polymerization, essential for cell migration and morphogenesis. Dysregulation of NCKAP is associated with several diseases, including cancer and neurological disorders.
NCKAP is a multidomain protein with several critical regions:
NCKAP proteins are large, typically over 1,000 amino acids, and their structure allows them to act as scaffolds, bringing together various proteins to regulate actin dynamics.
NCKAP proteins are part of a family that includes different isoforms:
NCKAP proteins are crucial regulators of the actin cytoskeleton, participating in essential cellular functions such as migration, adhesion, and signaling. These proteins act as scaffolds within the WAVE complex, promoting actin polymerization in response to extracellular signals. The proper function of NCKAP proteins is vital for normal cellular processes, and their dysregulation is implicated in various diseases, including cancer, neurological disorders, and immunodeficiencies. Understanding the structure and function of NCKAP proteins is fundamental for elucidating their role in health and disease.
NCK associated protein 1 (NCKAP1)
HEM2,NAP1,NAP125,p125Nap1,Membrane-associated protein HEM-2
NCK associated protein 1 like (NCKAP1L)
HEM1,IMD72,Hematopoietic protein 1,Membrane-associated protein HEM-1
NCK associated protein 5 (NCKAP5)
ERIH,NAP5,ERIH1,ERIH2,Peripheral clock protein,
NCK associated protein 5 like (NCKAP5L)
Cep169,FP1193,KIAA1602,NCKAP5-like,Centrosomal protein of 169 kDa
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits) relacionados con NCKAP - NCK associated protein
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 15 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | NCKAP1 | abx381706 | Human NCK Associated Protein 1 (NCKAP1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.065 ng/ml | 687.5 | 96 tests | Q9Y2A7 | RUO |
Abbexa | NCKAP1L | abx534669 | Human Nck-associated protein 1-like (NCKAP1L) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P55160 | RUO | ||
Abbexa | NCKAP5 | abx534668 | Human Nck-associated protein 5 (NCKAP5) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | O14513 | RUO | ||
Abbexa | NCKAP5L | abx388133 | Human KIAA1602 (NCKAP5L) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.313 ng/ml - 20 ng/ml | < 0.188 ng/ml | 687.5 | 96 tests | Q9HCH0 | RUO |
Abbexa | NCKAP1 | abx389992 | Mouse Nck-associated protein 3 (NCKAP1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | < 46.9 pg/ml | 687.5 | 96 tests | P28660 | RUO |
Abbexa | NCKAP5L | abx534664 | Mouse Nck-associated protein 5-like (NCKAP5L) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q6GQX2 | RUO | ||
Abbexa | NCKAP1 | abx391670 | Rat Nck-associated protein 1 (NCKAP1) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.094 ng/ml | 687.5 | 96 tests | P55161 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | NCKAP1 | abx431956 | Nck-Associated Protein 3 (NCKAP1) Antibody | Polyclonal | Goat | Nck-Associated Protein 3 (NCKAP1) | Unconjugated | P-ELISA | 387.5 | 200 µl | RUO | |||
FineTest | NCKAP1 | FNab05585 | anti- NCKAP1 antibody | human | polyclonal | Rabbit | NCK-associated protein 1 | IgG | Unconjugated | ELISA, WB, IHC | 100µg | Q9Y2A7 | RUO | |
Abbexa | NCKAP1 | abx032664 | Nck-Associated Protein 3 (NCKAP1) Antibody | Human | Polyclonal | Rabbit | Nck-Associated Protein 3 (NCKAP1) | Unconjugated | ELISA, WB | 250 | 80 µl | Q9Y2A7 | RUO | |
Abbexa | NCKAP1 | abx126227 | Nck-Associated Protein 3 (NCKAP1) Antibody | Human | Polyclonal | Rabbit | Nck-Associated Protein 3 (NCKAP1) | Unconjugated | WB | 175 | 20 µl | Q9Y2A7 | RUO | |
Abbexa | NCKAP1 | abx235585 | Nck-Associated Protein 3 (NCKAP1) Antibody | Human | Polyclonal | Rabbit | Nck-Associated Protein 3 (NCKAP1) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | Q9Y2A7 | RUO | |
Abbexa | NCKAP1 | abx213880 | Nck-associated protein 3 (NCKAP1) Antibody | Human | Polyclonal | Rabbit | Nck-associated protein 3 (NCKAP1) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9Y2A7 | RUO | |
Abbexa | NCKAP1 | abx114032 | Nck-Associated Protein 1 (NCKAP1) Antibody | Human | Polyclonal | Rabbit | Nck-Associated Protein 1 (NCKAP1) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | Q9Y2A7 | RUO | |
Abbexa | NCKAP1 | abx213879 | Nck-associated protein 3 (NCKAP1) Antibody | Human | Polyclonal | Rabbit | Nck-associated protein 3 (NCKAP1) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9Y2A7 | RUO |
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