Family main features
Lipopolysaccharides (LPS) are large molecules found in the outer membrane of Gram-negative bacteria. They are a key component of the bacterial cell wall and play a crucial role in bacterial structure, integrity, and protection. LPS molecules consist of three main components:Lipid A: The innermost region of LPS, lipid A, anchors the molecule to the bacterial cell membrane. It consists of a phosphorylated diglucosamine backbone with multiple fatty acid chains. Lipid A is responsible for the endotoxic properties of LPS and is recognized by the host immune system. Core Oligosaccharide: The core oligosaccharide is a short chain of sugars attached to lipid A. It varies in composition among different bacterial species and strains. O-antigen (O-specific polysaccharide): The O-antigen is a long chain of repeating sugar units extending from the core oligosaccharide. It forms the outermost region of LPS and exhibits considerable variability among bacterial strains, contributing to the diversity of LPS structures. LPS helps maintain the structural integrity of the bacterial cell wall, protecting the bacterium from environmental stresses and host immune defenses. LPS is recognized by the host immune system as a microbial "signature" molecule, or pathogen-associated molecular pattern (PAMP). It activates the innate immune response via pattern recognition receptors (PRRs), such as Toll-like receptor 4 (TLR4), CD14, and MD-2, leading to the production of pro-inflammatory cytokines, chemokines, and other mediators of inflammation. Lipid A, the lipid component of LPS, is responsible for the endotoxic effects of LPS. Upon recognition by host immune cells, particularly macrophages and monocytes, lipid A triggers a potent inflammatory response characterized by fever, cytokine release, vasodilation, and activation of the coagulation cascade. Excessive or uncontrolled release of cytokines can lead to systemic inflammation, septic shock, and multiple organ dysfunction syndrome (MODS)LPS is a major contributor to the pathogenesis of sepsis, a life-threatening condition characterized by systemic inflammation and organ dysfunction in response to microbial infection. In severe cases, the systemic release of LPS can lead to septic shock, a medical emergency with high mortality rates.
LPS are not proteins, but rather complex molecules composed of three parts:
LPS are classified based on the structure of their O-antigen and the variations in their core oligosaccharides. These variations can affect the virulence and immune recognition of the bacteria. Different bacteria have different O-antigen structures, which can be used to distinguish between bacterial strains.
Lipopolysaccharides (LPS) are essential components of the outer membrane of Gram-negative bacteria, playing a significant role in maintaining membrane integrity and protecting against environmental threats. However, they also act as potent endotoxins, capable of triggering strong immune responses. LPS interactions with immune receptors such as TLR4 are crucial for initiating defense mechanisms against bacterial infections but can also lead to severe conditions like septic shock when present in large quantities. Understanding LPS structure and function is vital for developing treatments for bacterial infections and inflammatory diseases associated with endotoxin exposure.
Lipopolysaccharides (LPS)
PLS
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits, CLIA Kits) relacionados con LPS - Lipopolysaccharides
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Esta página contiene 44 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | LPS | abx150357 | Lipopolysaccharides (LPS) ELISA Kit | General | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Competitive | 12.35 ng/ml - 1000 ng/ml | < 5.53 ng/ml | 743.75 | 96 tests | RUO | |
Abbexa | LPS | abx052841 | Low Sample Volume Lipopolysaccharides (LPS) ELISA Kit | General | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. | Competitive | 12.35 ng/ml - 1000 ng/ml | < 4.53 ng/ml | 743.75 | 96 tests | RUO | |
Abbexa | LPS | abx355419 | Low Sample Volume Lipopolysaccharides (LPS) ELISA Kit | General | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.47 ng/ml - 30 ng/ml | < 0.19 ng/ml | 775 | 96 tests | RUO | |
Abbexa | LPS | abx490422 | Lipopolysaccharides (LPS) CLIA Kit | General | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. | Competitive | 12.35 ng/ml - 1000 ng/ml | < 4.93 ng/ml | 950 | 96 tests | RUO | |
Abbexa | LPS | abx517692 | Lipopolysaccharides (LPS) ELISA Kit | General | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 7.8 pg/ml - 500 pg/ml | < 3.5 pg/ml | 556.25 | 96 tests | RUO | |
Abbexa | LPS | abx574126 | Lipopolysaccharides (LPS) ELISA Kit | General | Serum,Plasma,Other biological fluids | Competitive | 0.78 ng/ml - 50 ng/ml | 0.47 ng/ml | 556.25 | 96 tests | RUO | |
Abbexa | LPS | abx585153 | Lipopolysaccharides (LPS) ELISA Kit | General | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.47 ng/ml - 30 ng/ml | < 0.17 ng/ml | 662.5 | 96 tests | RUO | |
Abbexa | LPS | abx585204 | Lipopolysaccharides (LPS) ELISA Kit | General | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.07 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | LPS | abx251920 | Human Lipopolysaccharides (LPS) ELISA Kit | Human | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. | Sandwich | 0.47 ng/ml - 30 ng/ml | < 0.2 ng/ml | 662.5 | 96 tests | RUO | |
Abbexa | LPS | abx051542 | Mouse Lipopolysaccharides / Endotoxin (LPS / ET) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.47 ng/ml - 30 ng/ml | < 0.17 ng/ml | 618.75 | 96 tests | RUO | |
FineTest | LPS | EU3126 | LPS(Lipopolysaccharides) ELISA Kit | universal | Serum,Plasma,Tissue homogenates,Other biological fluids | Competitive ELISA, Coated with Antibody | 0.313-20ug/ml | 96T | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | LPS | abx024036 | Legionella pneumophila LPS Antibody | Monoclonal | Mouse | Legionella pneumophila LPS | ELISA, LF | 1050 | 1 mg | RUO | ||||
Abbexa | LPS | abx024037 | Legionella pneumophila LPS Antibody | Monoclonal | Mouse | Legionella pneumophila LPS | ELISA, LF | 1050 | 1 mg | RUO | ||||
Abbexa | LPS | abx411209 | Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Chlamydia trachomatis Lipopolysaccharide (LPS) | Unconjugated | ELISA, WB | 487.5 | 200 µg | RUO | ||
Abbexa | LPS | abx411210 | Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Chlamydia trachomatis Lipopolysaccharide (LPS) | Unconjugated | ELISA, WB | 487.5 | 200 µg | RUO | ||
Abbexa | LPS | abx411324 | Escherichia coli J5 Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Escherichia coli J5 Lipopolysaccharide (LPS) | Unconjugated | ELISA, WB | 350 | 100 µg | RUO | ||
Abbexa | LPS | abx414518 | Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Chlamydia trachomatis Lipopolysaccharide (LPS) | Unconjugated | ELISA, WB, IF/ICC | 775 | 1 mg | RUO | ||
Abbexa | LPS | abx414622 | Salmonella Paratyphi Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Salmonella Paratyphi Lipopolysaccharide (LPS) | Unconjugated | ELISA, WB, IF/ICC | 487.5 | 200 µg | RUO | ||
Abbexa | LPS | abx415687 | Bordetella pertussis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Bordetella pertussis Lipopolysaccharide (LPS) | Unconjugated | ELISA, WB, IF/ICC | 600 | 100 µg | RUO | ||
Abbexa | LPS | abx415762 | Escherichia coli Lipopolysaccharide (LPS) Antibody | Bacteria | Polyclonal | Goat | Escherichia coli Lipopolysaccharide (LPS) | Unconjugated | IF/ICC | 537.5 | 1 ml | RUO | ||
Abbexa | LPS | abx022036 | Legionella pneumophila Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Legionella pneumophila Lipopolysaccharide (LPS) | Unconjugated | ELISA, IF/ICC | 1550 | 1 mg | RUO | ||
Abbexa | LPS | abx022227 | Salmonella Typhimurium Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Salmonella Typhimurium Lipopolysaccharide (LPS) | Unconjugated | ELISA | 775 | 1 mg | RUO | ||
Abbexa | LPS | abx022037 | Legionella pneumophila Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Legionella pneumophila Lipopolysaccharide (LPS) | Unconjugated | ELISA | 700 | 1 mg | RUO | ||
Abbexa | LPS | abx022039 | Legionella pneumophila Lipopolysaccharide (LPS) Antibody (Biotin) | Bacteria | Monoclonal | Mouse | Legionella pneumophila Lipopolysaccharide (LPS) | Biotin | ELISA | 1512.5 | 1 mg | RUO | ||
Abbexa | LPS | abx022038 | Legionella pneumophila Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Legionella pneumophila Lipopolysaccharide (LPS) | Unconjugated | ELISA | 700 | 1 mg | RUO | ||
Abbexa | LPS | abx022225 | Salmonella Typhimurium Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Salmonella Typhimurium Lipopolysaccharide (LPS) | Unconjugated | ELISA, IF/ICC, LF | 1200 | 1 mg | RUO | ||
Abbexa | LPS | abx022035 | Legionella pneumophila Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Legionella pneumophila Lipopolysaccharide (LPS) | Unconjugated | ELISA, IF/ICC | 1550 | 1 mg | RUO | ||
Abbexa | LPS | abx411459 | Escherichia coli J5 Lipopolysaccharide (LPS) Antibody | Bacteria | Polyclonal | Sheep | Escherichia coli J5 Lipopolysaccharide (LPS) | Unconjugated | ELISA | 425 | 1 ml | RUO | ||
Abbexa | LPS | abx411596 | Salmonella Enteritidis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Salmonella Enteritidis Lipopolysaccharide (LPS) | Unconjugated | ELISA, WB | 487.5 | 200 µg | RUO | ||
Abbexa | LPS | abx411597 | Salmonella Typhimurium Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Salmonella Typhimurium Lipopolysaccharide (LPS) | Unconjugated | ELISA, IF/ICC | 487.5 | 200 µg | RUO | ||
Abbexa | LPS | abx021587 | Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Chlamydia trachomatis Lipopolysaccharide (LPS) | Unconjugated | ELISA | 775 | 1 mg | RUO | ||
Abbexa | LPS | abx021598 | Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Chlamydia trachomatis Lipopolysaccharide (LPS) | Unconjugated | LF | 575 | 1 mg | RUO | ||
Abbexa | LPS | abx021599 | Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Chlamydia trachomatis Lipopolysaccharide (LPS) | Unconjugated | LF | 575 | 1 mg | RUO | ||
Abbexa | LPS | abx021581 | Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Chlamydia trachomatis Lipopolysaccharide (LPS) | Unconjugated | ELISA | 1150 | 100 µg | RUO | ||
Abbexa | LPS | abx021584 | Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Chlamydia trachomatis Lipopolysaccharide (LPS) | Unconjugated | ELISA, IHC-P, IF/ICC | 1200 | 1 mg | RUO | ||
Abbexa | LPS | abx021585 | Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody | Bacteria | Monoclonal | Mouse | Chlamydia trachomatis Lipopolysaccharide (LPS) | Unconjugated | ELISA, IHC-P, IF/ICC | 1200 | 1 mg | RUO | ||
Abbexa | LPS | abx274403 | Escherichia coli Lipopolysaccharide (LPS) Antibody (Biotin) | General | Polyclonal | Rabbit | Escherichia coli Lipopolysaccharide (LPS) | Biotin | ELISA | 400 | 200 µl | RUO | ||
Abbexa | LPS | abx274405 | Escherichia coli Lipopolysaccharide (LPS) Antibody (FITC) | General | Polyclonal | Rabbit | Escherichia coli Lipopolysaccharide (LPS) | FITC | ELISA | 475 | 200 µl | RUO | ||
Abbexa | LPS | abx370829 | Escherichia coli Lipopolysaccharide (LPS) Antibody Pair | General | Escherichia coli Lipopolysaccharide (LPS) | ELISA | 1425 | 5 × 96 tests | RUO | |||||
Abbexa | LPS | abx274406 | Escherichia coli Lipopolysaccharide (LPS) Antibody (FITC) | General | Monoclonal | Mouse | Escherichia coli Lipopolysaccharide (LPS) | FITC | ELISA | 325 | 100 µl | RUO | ||
Abbexa | LPS | abx101772 | Escherichia coli Lipopolysaccharide (LPS) Antibody | General | Monoclonal | Mouse | Escherichia coli Lipopolysaccharide (LPS) | Unconjugated | WB, IHC | 287.5 | 100 µl | RUO | ||
Abbexa | LPS | abx274404 | Escherichia coli Lipopolysaccharide (LPS) Antibody (Biotin) | General | Monoclonal | Mouse | Escherichia coli Lipopolysaccharide (LPS) | Biotin | ELISA | 287.5 | 100 µl | RUO | ||
Abbexa | LPS | abx175178 | Escherichia coli Lipopolysaccharide (LPS) Antibody | General | Monoclonal | Mouse | Escherichia coli Lipopolysaccharide (LPS) | Unconjugated | ELISA, WB, IHC, IF/ICC | 287.5 | 100 µl | RUO | ||
Abbexa | LPS | abx131271 | Escherichia coli Lipopolysaccharide (LPS) Antibody | General | Polyclonal | Rabbit | Escherichia coli Lipopolysaccharide (LPS) | Unconjugated | ELISA | 287.5 | 100 µl | RUO |
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