Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody
611€ (1 mg)
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935106861
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name
Chlamydia trachomatis Lipopolysaccharide (LPS) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx021599
tested applications
LF
Description
Mouse monoclonal antibody against LPS from C. trachomatis.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Chlamydia trachomatis Lipopolysaccharide (LPS) |
| Host | Mouse |
| Reactivity | Bacteria |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from ascites. |
| Size 1 | 1 mg |
| Form | Liquid |
| Tested Applications | LF |
| Buffer | Buffer contains NaN3 as a preservative. |
| Availability | Shipped within 10-20 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. |
| Dry Ice | No |
| Alias | LPS |
| Background | Antibody anti-LPS |
| Status | RUO |
Descripción
Lipopolysaccharides (LPS) are large molecules found in the outer membrane of Gram-negative bacteria, playing a crucial role in the structural integrity of bacterial cells and acting as a potent activator of the immune system. Composed of lipid A, a core oligosaccharide, and an O-antigen polysaccharide, LPS is a critical factor in bacterial pathogenicity. Lipid A is the bioactive component that triggers immune responses by binding to the Toll-like receptor 4 (TLR4) complex on immune cells, leading to the activation of nuclear factor-kappa B (NF-κB) and the release of pro-inflammatory cytokines such as IL-6 and TNF-alpha. While LPS is essential for host defense, its excessive activation can result in septic shock, characterized by systemic inflammation, organ failure, and high mortality. Therapeutic strategies targeting LPS-TLR4 signaling pathways are being explored to manage sepsis and other inflammatory conditions.
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