Family main features
APLNR, also known as the Apelin receptor or APJ, is a G protein-coupled receptor (GPCR) that was initially identified based on its sequence similarity to the angiotensin receptor. APLNR is encoded by the APLNR gene in humans and is widely expressed in various tissues, including the heart, lungs, kidneys, and central nervous system. This receptor is known to bind to the endogenous peptide ligand apelin and plays a significant role in numerous physiological processes.
APLNR is classified as a class A (rhodopsin-like) GPCR. Although there are no major subtypes of the APLNR receptor itself, the receptor can interact with various isoforms of its ligand apelin, such as apelin-13, apelin-17, and apelin-36, which can have differing physiological effects.
APLNR is a critical GPCR involved in a wide array of physiological processes, particularly in cardiovascular regulation, fluid homeostasis, and energy metabolism. The receptor's interaction with its ligand apelin mediates important signaling pathways that influence heart function, blood vessel formation, and metabolic balance. Dysregulation of the apelin-APLNR axis is implicated in several diseases, including cardiovascular diseases, metabolic disorders, cancer, and neurodegenerative diseases. Understanding the detailed mechanisms of APLNR signaling and its interactions with various ligands and intracellular proteins can provide insights into novel therapeutic strategies for these conditions.
Apelin Receptor (APLNR)
APLNR,angiotensin receptor-like 1,AGTRL1 ,APJ,APJR,angiotensin II receptor-like 1 ,B78,GPCR34 | G-protein coupled receptor APJ,APJR, HG11
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits, CLIA Kits) relacionados con APLNR - Apelin receptor
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 22 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | APLNR | abx521095 | Human Apelin Receptor (APLNR) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 687.5 | 96 tests | P35414 | RUO | |
FineTest | APLNR | EM6161 | Mouse Aplnr (Apelin receptor) ELISA Kit | mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 78.125-5000pg/ml | 96T | Q9WV08 | RUO | ||
Abbexa | APLNR | abx521096 | Mouse Apelin Receptor (APLNR) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 687.5 | 96 tests | Q9WV08 | RUO | |
FineTest | APLNR | ER0701 | Rat Aplnr(Apelin receptor) ELISA Kit | rat | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | Q9JHG3 | RUO | ||
Abbexa | APLNR | abx155213 | Rat Apelin Receptor (APLNR) ELISA Kit | Rat | Tissue homogenates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.13 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | APLNR | abx494074 | Rat Apelin Receptor (APLNR) CLIA Kit | Rat | Tissue homogenates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.128 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | APLNR | abx256676 | Rat Apelin Receptor (APLNR) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.78 ng/ml - 50 ng/ml | 0.47 ng/ml | 562.5 | 96 tests | Q9JHG3 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | APLNR | FNab00485 | anti- APLNR antibody | human | polyclonal | Rabbit | apelin receptor | IgG | Unconjugated | ELISA, WB, IHC | 100µg | P35414 | RUO | |
Abbexa | APLNR | abx002049 | Apelin Receptor (APLNR) Antibody | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | Unconjugated | WB | 175 | 20 µl | P35414 | RUO | |
Abbexa | APLNR | abx027815 | Apelin Receptor (APLNR) Antibody | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | Unconjugated | ELISA, WB | 250 | 80 µl | P35414 | RUO | |
Abbexa | APLNR | abx036754 | Apelin Receptor (APLNR) Antibody | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | P35414 | RUO | |
Abbexa | APLNR | abx301913 | Apelin Receptor (APLNR) Antibody | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | Unconjugated | ELISA, IHC, IF/ICC | 162.5 | 20 µg | P35414 | RUO | |
Abbexa | APLNR | abx303080 | Apelin Receptor (APLNR) Antibody (FITC) | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | FITC | 162.5 | 20 µg | P35414 | RUO | ||
Abbexa | APLNR | abx303081 | Apelin Receptor (APLNR) Antibody (Biotin) | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | Biotin | ELISA | 162.5 | 20 µg | P35414 | RUO | |
Abbexa | APLNR | abx324791 | Apelin Receptor (APLNR) Antibody | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | P35414 | RUO | |
Abbexa | APLNR | abx303079 | Apelin Receptor (APLNR) Antibody (HRP) | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | HRP | ELISA | 162.5 | 20 µg | P35414 | RUO | |
Abbexa | APLNR | abx214548 | Apelin Receptor (APLNR) Antibody | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | Unconjugated | ELISA, IHC | 250 | 50 µl | P35414 | RUO | |
Abbexa | APLNR | abx213965 | Apelin Receptor (APLNR) Antibody | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P35414 | RUO | |
Abbexa | APLNR | abx214549 | Apelin Receptor (APLNR) Antibody | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | Unconjugated | ELISA, IHC | 250 | 50 µl | P35414 | RUO | |
Abbexa | APLNR | abx230485 | Apelin Receptor (APLNR) Antibody | Human | Polyclonal | Rabbit | Apelin Receptor (APLNR) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | P35414 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | APLNR | abx652537 | Rat Apelin Receptor (APLNR) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 1800 | 1 mg | RUO | |
FineTest | APLNR | P2541 | Recombinant Human APLNR | Human | Recombinant | E.Coli | Western Blot, ELISA | 50μg | P35414 | RUO |
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