Apelin Receptor (APLNR) Antibody
proveedor
Abbexareference
abx324791Tested Applications
ELISA, WB, IHC, IF/ICCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
APLNR Antibody is a Rabbit Polyclonal against APLNR.
Background
The Apelin Receptor (APLNR), also known as APJ, is a G protein-coupled receptor. APLNR serves as the receptor for two endogenous ligands: APELIN and ELABELA. It plays a crucial role in early development processes such as gastrulation, the formation of blood vessels, and the morphogenesis of the heart, primarily by acting as a receptor for the APELA hormone. Additionally, APLNR may facilitate the migration of angioblasts toward the embryonic midline, which is the future site of vessel formation, during the process of vasculogenesis. This receptor-ligand interaction is essential for orchestrating these critical developmental events
Background
El receptor de Apelina (APLNR), también conocido como APJ, es un receptor acoplado a proteína G. APLNR sirve como receptor de dos ligandos endógenos: APELIN y ELABELA. Desempeña un papel crucial en los procesos tempranos del desarrollo como la gastrulación, la formación de vasos sanguíneos y la morfogénesis del corazón, principalmente actuando como receptor de la hormona APELA. Además, APLNR puede facilitar la migración de angioblastos hacia la línea media embrionaria, que es el futuro sitio de formación de vasos, durante el proceso de vasculogénesis. Esta interacción receptor-ligando es esencial para orquestar estos eventos críticos del desarrollo.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Apelin Receptor (APLNR)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC, IF/ICC
purification
Purified by affinity chromatography.
buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
size 1
50 µg
size 2
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
APLNR
dry ice
No
availability
Shipped within 5-10 working days.
alias
APLNR,angiotensin receptor-like 1,AGTRL1 ,APJ,APJR,angiotensin II receptor-like 1 ,B78,GPCR34 | G-protein coupled receptor APJ,APJR, HG11
uniprot id
note
This product is for research use only.
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