Family main features
Angiotensin converting enzyme (ACE) is a pivotal enzyme in the Renin-Angiotensin-Aldosterone System (RAAS), a key regulator of blood pressure and fluid balance in the body. ACE plays a crucial role in converting angiotensin I to angiotensin II, a potent vasoconstrictor, thereby increasing blood pressure. ACE inhibitors are commonly prescribed medications that block this conversion, leading to vasodilation and reduced blood pressure. Apart from its role in blood pressure regulation, ACE also has functions in the metabolism of other peptides, including bradykinin. Dysregulation of ACE activity is associated with various cardiovascular diseases, such as hypertension, heart failure, and myocardial infarction. ACE inhibitors are widely used in the management of hypertension, heart failure, and certain kidney diseases. ACE gene polymorphisms have been linked to differences in individual responses to ACE inhibitors and susceptibility to cardiovascular diseases. Understanding the role of ACE has led to the development of novel therapeutic strategies targeting the RAAS for the treatment of cardiovascular disorders.
ACE is a zinc metalloprotease with two main isoforms:
Key structural features include:
ACE belongs to the M2 family of metallopeptidases and is classified based on its domain structure:
ACE plays several critical roles in physiological processes:
ACE interacts with several molecules and proteins:
Dysregulation or inhibition of ACE has significant clinical implications:
Angiotensin I Converting Enzyme (ACE) is a pivotal enzyme in the renin-angiotensin system, playing a crucial role in the regulation of blood pressure and fluid balance. It converts angiotensin I into the potent vasoconstrictor angiotensin II and degrades the vasodilator bradykinin. ACE has two main isoforms: somatic ACE (sACE) with two catalytic domains and testicular ACE (tACE) with one catalytic domain. Dysregulation of ACE activity is associated with hypertension, heart failure, and chronic kidney disease, making it a critical target for therapeutic intervention using ACE inhibitors. Understanding the structure, function, and clinical implications of ACE is essential for managing cardiovascular and renal diseases.
Angiotensin I Converting Enzyme(ACE)
ACE1,CD143,DCP,DCP1,ICH,MVCD3
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, CLIA Kits, Primary Antibodies) relacionados con ACE - Angiotensin I Converting Enzyme
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 64 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ACE | abx511333 | Chicken Angiotensin I Converting Enzyme (ACE) ELISA Kit | Chicken | Tissue homogenates,Cell lysates,Other biological fluids | 0.312 ng/ml - 20 ng/ml | < 0.15 ng/ml | 687.5 | 96 tests | Q10751 | RUO | |
Abbexa | ACE | abx490747 | Cow Angiotensin I Converting Enzyme (ACE) CLIA Kit | Cow | Serum, plasma and other biological fluids. | Sandwich | 6.25 ng/ml - 400 ng/ml | < 2.15 ng/ml | 812.5 | 96 tests | Q9BDG1 | RUO |
Abbexa | ACE | abx150057 | Cow Angiotensin I Converting Enzyme (ACE) ELISA Kit | Cow | Serum,Plasma,Other biological fluids | Sandwich | 6.25 ng/ml - 400 ng/ml | < 2.15 ng/ml | 712.5 | 96 tests | Q9BDG1 | RUO |
Abbexa | ACE | abx250091 | Guinea pig Angiotensin I Converting Enzyme (ACE) ELISA Kit | Guinea pig | Serum, plasma, other biological fluids | Sandwich | 0.313 ng/ml - 20 ng/ml | < 0.19 ng/ml | 687.5 | 96 tests | RUO | |
FineTest | ACE | EH0026 | Human ACE(Angiotensin I Converting Enzyme) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.781-50ng/ml | 96T | P12821 | RUO | ||
Abbexa | ACE | abx195035 | Human Angiotensin I Converting Enzyme (ACE) CLIA Kit | Human | Serum, plasma and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | 0.1 ng/ml | 618.75 | 96 tests | RUO | |
Abbexa | ACE | abx150519 | Human Angiotensin I Converting Enzyme (ACE) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.39 ng/ml - 25 ng/ml | < 0.16 ng/ml | 575 | 96 tests | P12821 | RUO |
Abbexa | ACE | abx190035 | Human Angiotensin I Converting Enzyme (ACE) CLIA Kit | Human | Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. | Sandwich | 68.6 pg/ml - 50000 pg/ml | < 25.4 pg/ml | 812.5 | 96 tests | RUO | |
Abbexa | ACE | abx050001 | Human Angiotensin I Converting Enzyme (ACE) ELISA Kit | Human | Serum,Plasma,Other biological fluids | Sandwich | 78.13 pg/ml - 5000 pg/ml | 46.9 pg/ml | 525 | 96 tests | P12821 | RUO |
Abbexa | ACE | abx255333 | Monkey Angiotensin I Converting Enzyme (ACE) ELISA Kit | Monkey | Serum, plasma and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | 0.1 ng/ml | 687.5 | 96 tests | RUO | |
FineTest | ACE | EM0011 | Mouse ACE(Angiotensin I Converting Enzyme) ELISA Kit | mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | P09470 | RUO | ||
Abbexa | ACE | abx053886 | Mouse Angiotensin I Converting Enzyme (ACE) ELISA Kit | Mouse | Serum,Plasma,Other biological fluids | Sandwich | 15.63 pg/ml - 1000 pg/ml | 9.38 pg/ml | 525 | 96 tests | RUO | |
Abbexa | ACE | abx190423 | Mouse Angiotensin I Converting Enzyme (ACE) CLIA Kit | Mouse | Serum, plasma, tissue homogenates, cell lysates, cerebrospinal fluid, cell culture supernatants and other biological fluids. | Sandwich | 54.9 pg/ml - 40000 pg/ml | < 21.5 pg/ml | 812.5 | 96 tests | RUO | |
Abbexa | ACE | abx153586 | Mouse Angiotensin I Converting Enzyme (ACE) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.15 ng/ml | 587.5 | 96 tests | P09470 | RUO |
Abbexa | ACE | abx195036 | Mouse Angiotensin I Converting Enzyme (ACE) CLIA Kit | Mouse | Serum, plasma and other biological fluids. | Sandwich | 62.5 pg/ml - 4000 pg/ml | 37.5 pg/ml | 618.75 | 96 tests | RUO | |
Abbexa | ACE | abx154877 | Pig Angiotensin I Converting Enzyme (ACE) ELISA Kit | Pig | Serum,Plasma,Other biological fluids | Sandwich | 31.2 pg/ml - 2000 pg/ml | < 12.2 pg/ml | 712.5 | 96 tests | A1YQ85 | RUO |
Abbexa | ACE | abx490748 | Pig Angiotensin I Converting Enzyme (ACE) CLIA Kit | Pig | Serum, plasma and other biological fluids. | Sandwich | 31.25 pg/ml - 2000 pg/ml | < 11.2 pg/ml | 812.5 | 96 tests | A1YQ85 | RUO |
Abbexa | ACE | abx155028 | Rabbit Angiotensin I Converting Enzyme (ACE) ELISA Kit | Rabbit | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.13 ng/ml | 675 | 96 tests | P12822 | RUO |
Abbexa | ACE | abx490750 | Rabbit Angiotensin I Converting Enzyme (ACE) CLIA Kit | Rabbit | Serum, plasma and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.128 ng/ml | 812.5 | 96 tests | P12822 | RUO |
FineTest | Ace | ER0094 | Rat Ace(Angiotensin-converting enzyme) ELISA Kit | rat | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | P47820 | RUO | ||
Abbexa | ACE | abx255667 | Rat Angiotensin I Converting Enzyme (ACE) ELISA Kit | Rat | Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 587.5 | 96 tests | P47820 | RUO |
Abbexa | ACE | abx490749 | Rat Angiotensin I Converting Enzyme (ACE) CLIA Kit | Rat | Serum, plasma, cerebrospinal fluid and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.122 ng/ml | 812.5 | 96 tests | P47820 | RUO |
Abbexa | ACE | abx155131 | Rat Angiotensin I Converting Enzyme (ACE) ELISA Kit | Rat | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.13 ng/ml | 675 | 96 tests | P47820 | RUO |
Abbexa | ACE | abx257098 | Sheep Angiotensin I Converting Enzyme (ACE) ELISA Kit | Sheep | Serum, plasma and other biological fluids. | Sandwich | 0.78 ng/ml - 50 ng/ml | 0.47 ng/ml | 687.5 | 96 tests | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | ACE | FNab00080 | anti- ACE antibody | human | polyclonal | Rabbit | angiotensin I converting enzyme(peptidyl-dipeptidase A) 1 | IgG | Unconjugated | ELISA, WB | 100µg | P12821 | RUO | |
Abbexa | ACE | abx037354 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, WB | 337.5 | 100 µg | RUO | ||
Abbexa | ACE | abx128667 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | WB, IHC, IF/ICC | 237.5 | 100 µl | P12821 | RUO | |
Abbexa | ACE | abx270178 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | FCM | 300 | 50 tests | RUO | ||
Abbexa | ACE | abx270179 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | FCM | 300 | 50 tests | RUO | ||
Abbexa | ACE | abx378001 | Angiotensin Ⅰ Converting Enzyme (ACE) Antibody Pair | Human | Angiotensin Ⅰ Converting Enzyme (ACE) | ELISA | 525 | 5 × 96 tests | P12821 | RUO | ||||
Abbexa | ACE | abx103103 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | WB, IHC, IF/ICC | 237.5 | 100 µl | P12821 | RUO | |
Abbexa | ACE | abx402203 | Angiotensin-converting enzyme (ACE) Antibody | Human | Monoclonal | Rabbit | Angiotensin-converting enzyme (ACE) | Unconjugated | ELISA, IHC | 287.5 | 50 µl | P12821 | RUO | |
Abbexa | ACE | abx140499 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Monoclonal | Mouse | Angiotensin I Converting Enzyme (ACE) | Unconjugated | FCM | 275 | 0.1 mg | P12821 | RUO | |
Abbexa | ACE | abx171229 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Monoclonal | Mouse | Angiotensin I Converting Enzyme (ACE) | Unconjugated | WB, IHC, IF/ICC | 637.5 | 1 ml | RUO | ||
Abbexa | ACE | abx033685 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, WB | 281.25 | 80 µl | P12821 | RUO | |
Abbexa | ACE | abx325361 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, IHC | 187.5 | 50 µg | P12821 | RUO | |
Abbexa | ACE | abx230080 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, WB | 350 | 100 µg | P12821 | RUO | |
Abbexa | ACE | abx241727 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P12821 | RUO | |
Abbexa | ACE | abx241081 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, WB | 250 | 50 µl | P12821 | RUO | |
Abbexa | ACE | abx214211 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P12821 | RUO | |
Abbexa | ACE | abx159297 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Monoclonal | Mouse | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, WB | 437.5 | 100 µl | P12821 | RUO | |
Abbexa | ACE | abx007261 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | WB, IHC | 175 | 20 µl | P12821 | RUO | |
Abbexa | ACE | abx328371 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | P12821 | RUO | |
Abbexa | ACE | abx241080 | Angiotensin I Converting Enzyme (ACE) Antibody | Human | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, WB | 250 | 50 µl | P12821 | RUO | |
Abbexa | ACE | abx103104 | Angiotensin I Converting Enzyme (ACE) Antibody | Mouse | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | WB, IHC, IF/ICC | 237.5 | 100 µl | P09470 | RUO | |
Abbexa | ACE | abx025482 | Angiotensin I Converting Enzyme (ACE) Antibody | Mouse | Monoclonal | Mouse | Angiotensin I Converting Enzyme (ACE) | Unconjugated | ELISA, WB | 518.75 | 100 µl | P12821 | RUO | |
Abbexa | ACE | abx129494 | Angiotensin I Converting Enzyme (ACE) Antibody | Mouse | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | WB, IHC, IF/ICC | 237.5 | 100 µl | P09470 | RUO | |
Abbexa | ACE | abx129607 | Angiotensin I Converting Enzyme (ACE) Antibody | Mouse | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | WB, IHC, IF/ICC | 237.5 | 100 µl | P09470 | RUO | |
Abbexa | ACE | abx171233 | Angiotensin I Converting Enzyme (ACE) Antibody | Pig | Monoclonal | Mouse | Angiotensin I Converting Enzyme (ACE) | Unconjugated | WB, IHC, IF/ICC | 850 | 1 ml | RUO | ||
Abbexa | ACE | abx103105 | Angiotensin I Converting Enzyme (ACE) Antibody | Pig | Polyclonal | Rabbit | Angiotensin I Converting Enzyme (ACE) | Unconjugated | WB, IHC, IF/ICC | 287.5 | 100 µl | F1RRW5 | RUO | |
Abbexa | ACE | abx341173 | Angiotensin-converting enzyme (ACE) Antibody (FITC) | Rat | Polyclonal | Rabbit | Angiotensin-converting enzyme (ACE) | FITC | 250 | 50 µl | P47820 | RUO | ||
Abbexa | ACE | abx341171 | Angiotensin-converting enzyme (ACE) Antibody | Rat | Polyclonal | Rabbit | Angiotensin-converting enzyme (ACE) | Unconjugated | ELISA, IHC | 250 | 50 µl | P47820 | RUO | |
Abbexa | ACE | abx341172 | Angiotensin-converting enzyme (ACE) Antibody (HRP) | Rat | Polyclonal | Rabbit | Angiotensin-converting enzyme (ACE) | HRP | ELISA | 250 | 50 µl | P47820 | RUO | |
Abbexa | ACE | abx341174 | Angiotensin-converting enzyme (ACE) Antibody (Biotin) | Rat | Polyclonal | Rabbit | Angiotensin-converting enzyme (ACE) | Biotin | ELISA | 250 | 50 µl | P47820 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ACE | abx652517 | Rat Angiotensin I Converting Enzyme (ACE) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 1800 | 1 mg | RUO | |
Abbexa | ACE | abx065347 | Pig Angiotensin I Converting Enzyme (ACE) Protein | Pig | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 400 | 50 µg | F1RRW5 | RUO |
Abbexa | ACE | abx167239 | Mouse Angiotensin I Converting Enzyme (ACE) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | P09470 | RUO |
Abbexa | ACE | abx166467 | Human Angiotensin I Converting Enzyme (ACE) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | P12821 | RUO |
Abbexa | ACE | abx065346 | Mouse Angiotensin I Converting Enzyme (ACE) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | P09470 | RUO |
Abbexa | ACE | abx652061 | Rabbit Angiotensin I Converting Enzyme (ACE) Protein | Rabbit | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 2475 | 1 mg | P12822 | RUO |
FineTest | ACE | P8059 | Recombinant Human ACE | Human | Recombinant | HEK 293 cells | Western Blot, ELISA | 50μg | Q9BYF1 | RUO | ||
Abbexa | ACE | abx065345 | Human Angiotensin I Converting Enzyme (ACE) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | P12821 | RUO |
Abbexa | ACE | abx065348 | Mouse Angiotensin I Converting Enzyme (ACE) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | P09470 | RUO |
Abbexa | ACE | abx652518 | Cow Angiotensin I Converting Enzyme (ACE) Protein | Cow | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 2112.5 | 1 mg | RUO |
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