Angiotensin I Converting Enzyme (ACE) Antibody
357.5€ (100 µg)
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935106861
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name
Angiotensin I Converting Enzyme (ACE) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037354
tested applications
ELISA, WB
Description
Rabbit Polyclonal against the ACE protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Angiotensin I Converting Enzyme (ACE) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ACE1,CD143,DCP,DCP1,ICH,MVCD3 |
| Background | Antibody anti-ACE |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Angiotensin converting enzyme (ACE) is a pivotal enzyme in the Renin-Angiotensin-Aldosterone System (RAAS), a key regulator of blood pressure and fluid balance in the body. ACE plays a crucial role in converting angiotensin I to angiotensin II, a potent vasoconstrictor, thereby increasing blood pressure. ACE inhibitors are commonly prescribed medications that block this conversion, leading to vasodilation and reduced blood pressure. Apart from its role in blood pressure regulation, ACE also has functions in the metabolism of other peptides, including bradykinin. Dysregulation of ACE activity is associated with various cardiovascular diseases, such as hypertension, heart failure, and myocardial infarction. ACE inhibitors are widely used in the management of hypertension, heart failure, and certain kidney diseases. ACE gene polymorphisms have been linked to differences in individual responses to ACE inhibitors and susceptibility to cardiovascular diseases. Understanding the role of ACE has led to the development of novel therapeutic strategies targeting the RAAS for the treatment of cardiovascular disorders.
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