Family main features
ADAMTS8 has a multi-domain structure characteristic of the ADAMTS family:
ADAMTS8 belongs to the ADAMTS family, characterized by the presence of TSP1 motifs and metalloprotease domains. It does not have distinct subtypes but shares functional and structural similarities with other ADAMTS enzymes involved in ECM degradation and remodeling.
ADAMTS8 is involved in several key biological processes:
ADAMTS8 interacts with various proteins and cellular components:
ADAMTS8 has potential clinical implications in various contexts:
ADAMTS8 is a crucial enzyme in the ADAMTS family, primarily involved in ECM remodeling and angiogenesis inhibition. Its multi-domain structure, including the metalloprotease and TSP1 domains, enables it to interact with various ECM components and cellular receptors. ADAMTS8 plays essential roles in maintaining tissue integrity and regulating angiogenesis, inflammation, and potentially tumor suppression. Understanding its structure, functions, interactions, and clinical implications provides valuable insights into its roles in various physiological and pathological processes.
ADAM metallopeptidase with thrombospondin type 1 motif 8(ADAMTS8)
METH2,Type 1 Motif 8,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 8,ADAM-TS 8,ADAM-TS8
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits, CLIA Kits) relacionados con ADAMTS8- ADAM metallopeptidase with thrombospondin type 1 motif 8
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 11 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | ADAMTS8 | EH1582 | Human ADAMTS8(A disintegrin and metalloproteinase with thrombospondin motifs 8) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 15.625-1000pg/ml | 96T | Q9UP79 | RUO | ||
Abbexa | ADAMTS8 | abx156895 | Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.06 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | ADAMTS8 | abx250872 | Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) ELISA Kit | Human | Serum,Plasma,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 562.5 | 96 tests | Q9UP79 | RUO |
Abbexa | ADAMTS8 | abx495840 | Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) CLIA Kit | Human | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.063 ng/ml | 812.5 | 96 tests | RUO | |
FineTest | ADAMTS8 | EM1973 | Mouse ADAMTS8(A disintegrin and metalloproteinase with thrombospondin motifs 8) ELISA Kit | mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 15.625-1000pg/ml | 96T | P57110 | RUO | ||
Abbexa | ADAMTS8 | abx516832 | Mouse ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) ELISA Kit | Mouse | Serum,Plasma,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | 687.5 | 96 tests | P57110 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ADAMTS8 | abx432283 | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) Antibody | Polyclonal | Goat | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) | Unconjugated | P-ELISA | 250 | 200 µl | RUO | |||
Abbexa | ADAMTS8 | abx431898 | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) Antibody | Polyclonal | Goat | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) | Unconjugated | P-ELISA | 250 | 200 µl | RUO | |||
Abbexa | ADAMTS8 | abx104700 | A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8) Antibody | Human | Polyclonal | Rabbit | A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | Q9UP79 | RUO | |
Abbexa | ADAMTS8 | abx038229 | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) Antibody | Human | Polyclonal | Rabbit | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ADAMTS8 | abx065082 | Human A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | Q9UP79 | RUO |
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