Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) CLIA Kit
845€ (96 tests)
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935106861
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name
Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495840
tested applications
CLIA
Description
Human ADAMTS8 Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.063 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | METH2,Type 1 Motif 8,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 8,ADAM-TS 8,ADAM-TS8 |
| Background | CLIA Kits ADAMTS8 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADAMTS8 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 8) is another member of the ADAMTS family of proteases. Similar to other members of the ADAMTS family, ADAMTS8 contains several characteristic domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. These domains play essential roles in substrate recognition, protein-protein interactions, and enzymatic activity. ADAMTS8 is expressed in various tissues, including the brain, heart, cartilage, and skeletal muscle. Its expression pattern suggests potential roles in tissue development, maintenance, and remodeling. ADAMTS8 is involved in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, including proteoglycans and collagens. Additionally, ADAMTS8 has been implicated in angiogenesis, wound healing, and inflammation. Dysregulation of ADAMTS8 has been associated with several diseases and conditions. For example, ADAMTS8 has been implicated in cancer progression, where it may influence tumor growth, invasion, and metastasis through its effects on the ECM and angiogenesis. Additionally, mutations in the ADAMTS8 gene have been linked to certain developmental disorders and connective tissue diseases.
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