Mouse ADAMTS8(A disintegrin and metalloproteinase with thrombospondin motifs 8) ELISA Kit

Este producto es parte de ADAMTS8- ADAM metallopeptidase with thrombospondin type 1 motif 8
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935106861
info@markelab.com
name
Mouse ADAMTS8(A disintegrin and metalloproteinase with thrombospondin motifs 8) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM1973

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich ELISA, Double Antibody
Test Range
15.625-1000pg/ml
Size 1
96T
Sample Type
Serum,Plasma,Tissue homogenates,Other biological fluids
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 6 months
UniProt ID
P57110
Alias
METH2,Type 1 Motif 8,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 8,ADAM-TS 8,ADAM-TS8
Background
Elisa Kits ADAMTS8
Status
RUO

ADAMTS8 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 8) is another member of the ADAMTS family of proteases. Similar to other members of the ADAMTS family, ADAMTS8 contains several characteristic domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. These domains play essential roles in substrate recognition, protein-protein interactions, and enzymatic activity. ADAMTS8 is expressed in various tissues, including the brain, heart, cartilage, and skeletal muscle. Its expression pattern suggests potential roles in tissue development, maintenance, and remodeling. ADAMTS8 is involved in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, including proteoglycans and collagens. Additionally, ADAMTS8 has been implicated in angiogenesis, wound healing, and inflammation. Dysregulation of ADAMTS8 has been associated with several diseases and conditions. For example, ADAMTS8 has been implicated in cancer progression, where it may influence tumor growth, invasion, and metastasis through its effects on the ECM and angiogenesis. Additionally, mutations in the ADAMTS8 gene have been linked to certain developmental disorders and connective tissue diseases.

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