Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) ELISA Kit

Este producto es parte de ADAMTS8- ADAM metallopeptidase with thrombospondin type 1 motif 8
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715€ (96 tests)

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935106861
info@markelab.com
name
Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx156895
tested applications
ELISA

Description

Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetADAM Metallopeptidase With Thrombospondin Type 1 Motif 8 (ADAMTS8)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range0.156 ng/ml - 10 ng/ml
Sensitivity< 0.06 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
AliasMETH2,Type 1 Motif 8,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 8,ADAM-TS 8,ADAM-TS8
BackgroundElisa kits for ADAMTS8
StatusRUO
NoteValidity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

ADAMTS8 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 8) is another member of the ADAMTS family of proteases. Similar to other members of the ADAMTS family, ADAMTS8 contains several characteristic domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. These domains play essential roles in substrate recognition, protein-protein interactions, and enzymatic activity. ADAMTS8 is expressed in various tissues, including the brain, heart, cartilage, and skeletal muscle. Its expression pattern suggests potential roles in tissue development, maintenance, and remodeling. ADAMTS8 is involved in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, including proteoglycans and collagens. Additionally, ADAMTS8 has been implicated in angiogenesis, wound healing, and inflammation. Dysregulation of ADAMTS8 has been associated with several diseases and conditions. For example, ADAMTS8 has been implicated in cancer progression, where it may influence tumor growth, invasion, and metastasis through its effects on the ECM and angiogenesis. Additionally, mutations in the ADAMTS8 gene have been linked to certain developmental disorders and connective tissue diseases.

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