Family main features
Acylphosphatase (ACYP) is an enzyme involved in cellular energy metabolism, particularly in the hydrolysis of acylphosphate bonds. It catalyzes the conversion of acylphosphate to carboxylate and inorganic phosphate, playing a role in maintaining cellular energy balance. ACYP is widely distributed in various tissues, including muscle, liver, and brain, indicating its importance in diverse physiological processes. Research suggests that ACYP may also have non-metabolic functions, such as regulating calcium signaling and protein folding. Mutations in the ACYP gene have been associated with certain neurological disorders, highlighting its significance in human health. Understanding the enzymatic properties and biological functions of ACYP is essential for elucidating its role in cellular physiology and disease pathogenesis. Ongoing research aims to uncover novel therapeutic strategies targeting ACYP-related pathways for various disorders.
Acylphosphatases have a conserved protein structure characterized by:
ACYP enzymes are classified into two main types based on their tissue distribution and substrate specificity:
Acylphosphatase enzymes perform several critical functions:
Acylphosphatases interact with various molecules and proteins within the cell:
Dysfunction or abnormal expression of acylphosphatases can lead to various clinical conditions:
ACYP encodes acylphosphatases, small enzymes crucial for hydrolyzing acyl-phosphate bonds in various metabolic intermediates. These enzymes play essential roles in energy metabolism, regulating glycolysis and gluconeogenesis, maintaining energy homeostasis, and participating in detoxification processes. Key subtypes include ACYP1 and ACYP2, each with distinct tissue distributions and functions. Dysregulation or mutations in these enzymes can lead to clinical conditions such as hemolytic anemia, metabolic disorders, neurological conditions, muscle disorders, and cancer. Understanding the structure, function, interactions, and clinical implications of acylphosphatases provides valuable insights into their roles in cellular metabolism and potential therapeutic targets.
Acylphosphatase 1(ACYP1)
erythrocyte isozyme,Acylphosphate phosphohydrolase 1
Acylphosphatase 2(ACYP2)
Acylphosphate phosphohydrolase 2
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits) relacionados con ACYP - Acylphosphatase
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 30 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ACYP1 | abx385613 | Human Acylphosphatase 1 (ACYP1) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.313 ng/ml - 20 ng/ml | < 0.19 ng/ml | 687.5 | 96 tests | P07311 | RUO |
Abbexa | ACYP2 | abx385614 | Human Acylphosphatase 2 (ACYP2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.313 ng/ml - 20 ng/ml | < 0.19 ng/ml | 687.5 | 96 tests | P14621 | RUO |
Abbexa | ACYP1 | abx500972 | Mouse Acylphosphatase-1 (ACYP1) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P56376 | RUO | ||
Abbexa | ACYP2 | abx500977 | Mouse Acylphosphatase-2 (ACYP2) ELISA Kit | Mouse | Serum,Plasma,Tissue homogenates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P56375 | RUO | ||
Abbexa | ACYP2 | abx500980 | Rat Acylphosphatase 2 (ACYP2) ELISA Kit | Rat | Serum,Plasma,Tissue homogenates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | P35745 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | ACYP1 | FNab00133 | anti- ACYP1 antibody | human | polyclonal | Rabbit | acylphosphatase 1, erythrocyte(common) type | IgG | Unconjugated | ELISA, WB | 100µg | P07311 | RUO | |
FineTest | ACYP2 | FNab00134 | anti- ACYP2 antibody | human | polyclonal | Rabbit | acylphosphatase 2, muscle type | IgG | Unconjugated | ELISA, WB, IHC | 100µg | P14621 | RUO | |
Abbexa | ACYP1 | abx038066 | Acylphosphatase 1 (ACYP1) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 1 (ACYP1) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | ACYP1 | abx029491 | Acylphosphatase 1 (ACYP1) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 1 (ACYP1) | Unconjugated | ELISA, WB | 250 | 80 µl | P07311 | RUO | |
Abbexa | ACYP1 | abx432067 | ACYP1 (Isoform a) Antibody | Human | Polyclonal | Goat | ACYP1 (Isoform a) | Unconjugated | P-ELISA, WB, IHC | 387.5 | 200 µl | RUO | ||
Abbexa | ACYP1 | abx130603 | Acylphosphatase 1, Erythrocyte (ACYP1) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 1, Erythrocyte (ACYP1) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO | ||
Abbexa | ACYP1 | abx211698 | Acylphosphatase 1, Erythrocyte (ACYP1) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 1, Erythrocyte (ACYP1) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P07311 | RUO | |
Abbexa | ACYP1 | abx211971 | Acylphosphatase 1, Erythrocyte (ACYP1) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 1, Erythrocyte (ACYP1) | Unconjugated | ELISA, WB | 250 | 50 µl | P07311 | RUO | |
Abbexa | ACYP1 | abx110816 | Acylphosphatase 1, Erythrocyte (ACYP1) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 1, Erythrocyte (ACYP1) | Unconjugated | ELISA, WB | 612.5 | 100 µl | P07311 | RUO | |
Abbexa | ACYP1 | abx230133 | Acylphosphatase 1 (ACYP1) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 1 (ACYP1) | Unconjugated | ELISA, WB | 350 | 100 µg | P07311 | RUO | |
Abbexa | ACYP2 | abx315186 | Acylphosphatase 2 (ACYP2) Antibody (HRP) | Human | Polyclonal | Rabbit | Acylphosphatase 2 (ACYP2) | HRP | ELISA | 162.5 | 20 µg | P14621 | RUO | |
Abbexa | ACYP2 | abx037999 | Acylphosphatase 2 (ACYP2) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 2 (ACYP2) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | ACYP2 | abx302208 | Acylphosphatase 2 (ACYP2) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 2 (ACYP2) | Unconjugated | ELISA, IHC, IF/ICC | 162.5 | 20 µg | P14621 | RUO | |
Abbexa | ACYP2 | abx315188 | Acylphosphatase 2 (ACYP2) Antibody (Biotin) | Human | Polyclonal | Rabbit | Acylphosphatase 2 (ACYP2) | Biotin | ELISA | 162.5 | 20 µg | P14621 | RUO | |
Abbexa | ACYP2 | abx315187 | Acylphosphatase 2 (ACYP2) Antibody (FITC) | Human | Polyclonal | Rabbit | Acylphosphatase 2 (ACYP2) | FITC | 162.5 | 20 µg | P14621 | RUO | ||
Abbexa | ACYP2 | abx130602 | Acylphosphatase 2, Muscle (ACYP2) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 2, Muscle (ACYP2) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO | ||
Abbexa | ACYP2 | abx110817 | Acylphosphatase 2, Muscle (ACYP2) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 2, Muscle (ACYP2) | Unconjugated | ELISA, WB, IHC | 612.5 | 100 µl | P14621 | RUO | |
Abbexa | ACYP2 | abx230134 | Acylphosphatase 2 (ACYP2) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 2 (ACYP2) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | P14621 | RUO | |
Abbexa | ACYP2 | abx330125 | Acylphosphatase 2, Muscle (ACYP2) Antibody | Human | Polyclonal | Rabbit | Acylphosphatase 2, Muscle (ACYP2) | Unconjugated | ELISA, WB | 187.5 | 50 µg | P14621 | RUO | |
Abbexa | ACYP2 | abx130601 | Acylphosphatase 2, Muscle (ACYP2) Antibody | Mouse | Polyclonal | Rabbit | Acylphosphatase 2, Muscle (ACYP2) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ACYP1 | abx073195 | Human Acylphosphatase 1 (ACYP1) Protein | Human | Recombinant | E. coli | SDS-PAGE | 225 | 5 µg | P07311 | RUO | |
FineTest | ACYP1 | P4562 | Recombinant Human ACYP1 | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | P07311 | RUO | ||
Abbexa | ACYP1 | abx168872 | Human Acylphosphatase 1, Erythrocyte (ACYP1) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | P07311 | RUO |
Abbexa | ACYP2 | abx168873 | Human Acylphosphatase 2, Muscle (ACYP2) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 187.5 | 10 µg | P14621 | RUO |
Abbexa | ACYP2 | abx168874 | Mouse Acylphosphatase 2, Muscle (ACYP2) Protein | Mouse | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | P56375 | RUO |
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