Acylphosphatase 1 (ACYP1) Antibody

Este producto es parte de ACYP - Acylphosphatase
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292.5€ (80 µl)

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935106861
info@markelab.com
name
Acylphosphatase 1 (ACYP1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx029491
tested applications
ELISA, WB

Description

Acylphosphatase is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase, on the basis of their tissue localization. This gene encodes the erythrocyte acylphosphatase isoenzyme. Alternatively spliced transcript variants that encode different proteins were identified through data analysis. [provided by RefSeq].

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Acylphosphatase 1 (ACYP1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified through a protein A column, followed by peptide affinity purification.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P07311
Alias
erythrocyte isozyme,Acylphosphate phosphohydrolase 1
Background
Antibody anti-ACYP1
Status
RUO

Descripción

Acylphosphatase 1 (ACYP1) is a small cytosolic enzyme that catalyzes the hydrolysis of acyl-phosphate bonds in a variety of substrates, including 1,3-bisphosphoglycerate and carbamoyl phosphate. ACYP1 is primarily expressed in erythrocytes and the brain, where it is thought to play a role in maintaining energy homeostasis and regulating cellular metabolism. It may also influence signaling pathways by modulating the levels of phosphorylated intermediates. ACYP1 has been implicated in oxidative stress responses and apoptosis, as its dysregulation is associated with increased susceptibility to oxidative damage. Mutations or altered expression of ACYP1 may contribute to neurological disorders and metabolic diseases, though its precise physiological roles remain under investigation.

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