Family main features
YWHAZ, also known as 14-3-3 protein zeta/delta, is a member of the highly conserved 14-3-3 protein family, which plays a crucial role in various cellular processes. These proteins function as adaptors or scaffold proteins, facilitating protein-protein interactions by binding to phosphorylated serine/threonine residues on target proteins. The 14-3-3 proteins are involved in the regulation of numerous cellular pathways, including signal transduction, cell cycle control, apoptosis, and cellular stress responses. YWHAZ, specifically, is expressed ubiquitously and is implicated in essential functions such as neuronal development, synaptic plasticity, and the regulation of the cytoskeleton. Dysregulation of YWHAZ has been associated with several diseases, including cancer, neurological disorders, and metabolic conditions, highlighting its significance in maintaining cellular homeostasis and proper physiological functions.
YWHAZ is characterized by a highly conserved structure typical of 14-3-3 proteins, which includes:
YWHAZ belongs to the 14-3-3 protein family, which comprises seven isoforms in mammals: β, γ, ε, η, σ, τ, and ζ/δ (YWHAZ). Each isoform has specific and overlapping functions, contributing to a wide range of cellular processes. YWHAZ, also known as 14-3-3ζ, is closely related to the δ isoform and is sometimes referred to as 14-3-3ζ/δ.
YWHAZ is involved in several critical cellular functions:
Dysregulation of YWHAZ is associated with several pathological conditions:
YWHAZ (14-3-3 protein zeta/delta) is a vital adaptor protein involved in numerous cellular processes, including signal transduction, cell cycle regulation, apoptosis, neuronal development, and cytoskeletal organization. Its structure, featuring a conserved alpha-helical fold and phosphoserine/threonine-binding groove, allows it to interact with a wide range of phosphorylated target proteins. Dysregulation of YWHAZ is linked to various diseases, including cancer, neurological disorders, and metabolic conditions, highlighting its importance in maintaining cellular homeostasis. Understanding the molecular mechanisms of YWHAZ can provide insights into potential therapeutic targets for these diseases.
14-3-3 protein zeta/delta (YWHAZ)
YWHAZ, 14-3-3-zeta, HEL-S-3, HEL4, KCIP-1, YWHAD, HEL-S-93, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, POPCHAS
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, ELISA Kits, CLIA Kits) relacionados con YWHAZ - 14-3-3 protein zeta/delta
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Esta página contiene 35 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | YWHAZ | abx595002 | 14-3-3 Protein Zeta/Delta (YWHAZ) Cell ELISA Kit | Human | Cell ELISA | 493.75 | 96 tests | P63104 | RUO | |||
Abbexa | YWHAZ | abx495788 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAZ) CLIA Kit | Human | Serum, plasma, tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.116 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | YWHAZ | abx258054 | 14-3-3 Protein Zeta/Delta (YWHAZ) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.12 ng/ml | 687.5 | 96 tests | RUO | |
FineTest | YWHAZ | ER0532 | Rat Ywhaz(14-3-3 protein zeta/delta) ELISA Kit | rat | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 31.25-2000pg/ml | 96T | P63102 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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FineTest | YWHAZ | FNab09577 | anti- YWHAZ antibody | human | polyclonal | Rabbit | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | IgG | Unconjugated | ELISA, WB, IHC | 100µg | P63104 | RUO | |
Abbexa | YWHAZ | abx314230 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody (HRP) | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta (YWHAZ) | HRP | ELISA | 162.5 | 20 µg | P63104 | RUO | |
Abbexa | YWHAZ | abx314231 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody (FITC) | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta (YWHAZ) | FITC | 162.5 | 20 µg | P63104 | RUO | ||
Abbexa | YWHAZ | abx314232 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody (Biotin) | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta (YWHAZ) | Biotin | ELISA | 162.5 | 20 µg | P63104 | RUO | |
Abbexa | YWHAZ | abx175001 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz) Antibody | Human | Monoclonal | Mouse | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO | ||
Abbexa | YWHAZ | abx033913 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta (YWHAZ) | Unconjugated | ELISA, WB, IHC | 281.25 | 80 µl | P63104 | RUO | |
Abbexa | YWHAZ | abx104726 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO | ||
Abbexa | YWHAZ | abx272429 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz) Antibody (Biotin) | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz) | Biotin | WB, IHC, IF/ICC | 362.5 | 200 µl | RUO | ||
Abbexa | YWHAZ | abx033912 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta (YWHAZ) | Unconjugated | ELISA, WB, IHC, FCM | 281.25 | 80 µl | P63104 | RUO | |
Abbexa | YWHAZ | abx033911 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta (YWHAZ) | Unconjugated | ELISA, WB, IHC | 281.25 | 80 µl | P63104 | RUO | |
Abbexa | YWHAZ | abx317881 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta (YWHAZ) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | P63104 | RUO | |
Abbexa | YWHAZ | abx329728 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAZ) | Unconjugated | ELISA, WB, IHC, IF/ICC, IP | 187.5 | 50 µg | P63104 | RUO | |
Abbexa | YWHAZ | abx328430 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta Phospho-Thr232 (YWHAZ pT232) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta Phospho-Thr232 (YWHAZ pT232) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | P63104 | RUO | |
Abbexa | YWHAZ | abx329468 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta Phospho-Ser58 (YWHAZ pS58) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta Phospho-Ser58 (YWHAZ pS58) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | P63104 | RUO | |
Abbexa | YWHAZ | abx333458 | YWHAZ (pT232) Antibody | Human | Polyclonal | Rabbit | YWHAZ (pT232) | Unconjugated | ELISA, WB | 412.5 | 100 µl | P63104 | RUO | |
Abbexa | YWHAZ | abx007346 | 14-3-3 Protein Zeta/delta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/delta (YWHAZ) | Unconjugated | WB, IHC, IF/ICC | 175 | 20 µl | P63104 | RUO | |
Abbexa | YWHAZ | abx329148 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAZ) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | P63104 | RUO | |
Abbexa | YWHAZ | abx333177 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta Phospho-Ser58 (YWHAZ pS58) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta Phospho-Ser58 (YWHAZ pS58) | Unconjugated | ELISA, WB, IHC, IF/ICC | 412.5 | 100 µl | P63104 | RUO | |
Abbexa | YWHAZ | abx116388 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta (YWHAZ) | Unconjugated | ELISA, WB | 612.5 | 100 µl | P63104 | RUO | |
Abbexa | YWHAZ | abx327907 | YWHAZ / YWHAB (pS184 / 186) Antibody | Human | Polyclonal | Rabbit | YWHAZ/YWHAB (pS184/186) | Unconjugated | ELISA, WB | 187.5 | 50 µg | P63104, P31946 | RUO | |
Abbexa | YWHAZ | abx012400 | 14-3-3 Protein Zeta/Delta Phospho-Ser58 (YWHAZ pS58) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta Phospho-Ser58 (YWHAZ pS58) | Unconjugated | WB, IHC, IF/ICC | 43.75 | 10 µg | P63104 | RUO | |
Abbexa | YWHAZ | abx013883 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta (YWHAZ) | Unconjugated | ELISA, WB | 43.75 | 10 µg | P63104 | RUO | |
Abbexa | YWHAZ | abx341074 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody | Human | Monoclonal | Mouse | 14-3-3 Protein Zeta/Delta (YWHAZ) | Unconjugated | ELISA, WB, IHC, IF/ICC, FCM | 287.5 | 50 µl | P63104 | RUO | |
Abbexa | YWHAZ | abx000247 | YWHAZ (pS58) Antibody | Human | Polyclonal | Rabbit | YWHAZ (pS58) | Unconjugated | WB, IF/ICC | 325 | 50 µl | P63104 | RUO | |
Abbexa | YWHAZ | abx327346 | YWHAZ / YWHAB Antibody | Human | Polyclonal | Rabbit | YWHAZ/YWHAB | Unconjugated | ELISA, WB | 187.5 | 50 µg | P63104, P31946 | RUO | |
Abbexa | YWHAZ | abx328369 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAZ) | Unconjugated | ELISA, WB, IHC | 187.5 | 50 µg | P63104 | RUO | |
Abbexa | YWHAZ | abx239577 | 14-3-3 Protein Zeta/Delta (YWHAZ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Zeta/Delta (YWHAZ) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | P63104 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | YWHAZ | abx655406 | Rat Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 1800 | 1 mg | RUO | |
Abbexa | YWHAZ | abx069582 | Human Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz) Protein | Human | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | P63104 | RUO | |
FineTest | YWHAZ | P2221 | Recombinant Human YWHAZ | Human | Recombinant | E.Coli | Western Blot, ELISA | 50μg | P63104 | RUO | ||
Abbexa | YWHAZ | abx073595 | Human 14-3-3 Protein Zeta/Delta (YWHAZ) Protein | Human | Recombinant | E. coli | SDS-PAGE | 225 | 5 µg | P63104 | RUO |
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