14-3-3 Protein Zeta/Delta (YWHAZ) ELISA Kit

Este producto es parte de YWHAZ - 14-3-3 protein zeta/delta
14-3-3 Protein Zeta/Delta (YWHAZ) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits YWHAZ

proveedor

Abbexa

reference

abx258054

Tested Applications

ELISA

reactivity

Human, Mouse, Rat

status

RUO

clonality

Descripción

14-3-3 Protein Zeta/Delta (YWHAZ) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human, Mouse, Rat Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein zeta concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

YWHAZ, a member of the 14-3-3 protein family, is a highly conserved adaptor protein that regulates signal transduction by binding to phosphorylated serine/threonine residues on target proteins. It functions as a molecular scaffold, facilitating protein-protein interactions involved in diverse cellular processes, including cell cycle progression, apoptosis, and signal transduction. YWHAZ plays a role in regulating pathways such as PI3K/Akt, MAPK, and TGF-β, influencing cell survival, proliferation, and migration. It is abundantly expressed in the brain and immune tissues, where it is critical for neuronal development, synaptic plasticity, and stress responses. Dysregulation of YWHAZ is implicated in neurological disorders, cancer progression, and metabolic diseases due to its role in stabilizing oncogenic and signaling proteins. Knockout studies reveal defects in brain development, increased apoptosis, and impaired cell signaling, underscoring its essential role as a key regulator of cellular homeostasis and signaling pathways.

Características del producto

category

ELISA Kits


immunogen target

14-3-3 Protein Zeta/Delta (YWHAZ)


reactivity

Human, Mouse, Rat


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.12 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

YWHAZ, 14-3-3-zeta, HEL-S-3, HEL4, KCIP-1, YWHAD, HEL-S-93, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, POPCHAS


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

YWHAZ


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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