935106861
info@markelab.com
Precio
162.5€ (20 µg)
YWHAZ Antibody (HRP) is a Rabbit Polyclonal against YWHAZ conjugated to HRP.
YWHAZ, a member of the 14-3-3 protein family, is a highly conserved adaptor protein that regulates signal transduction by binding to phosphorylated serine/threonine residues on target proteins. It functions as a molecular scaffold, facilitating protein-protein interactions involved in diverse cellular processes, including cell cycle progression, apoptosis, and signal transduction. YWHAZ plays a role in regulating pathways such as PI3K/Akt, MAPK, and TGF-β, influencing cell survival, proliferation, and migration. It is abundantly expressed in the brain and immune tissues, where it is critical for neuronal development, synaptic plasticity, and stress responses. Dysregulation of YWHAZ is implicated in neurological disorders, cancer progression, and metabolic diseases due to its role in stabilizing oncogenic and signaling proteins. Knockout studies reveal defects in brain development, increased apoptosis, and impaired cell signaling, underscoring its essential role as a key regulator of cellular homeostasis and signaling pathways.
Primary Antibodies
Polyclonal
Human
14-3-3 Protein Zeta/Delta (YWHAZ)
Rabbit
HRP
Liquid
ELISA
> 95%
Purified by Protein G.
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
20 µg
50 µg
100 µg
200 µg
1 mg
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
YWHAZ
No
Shipped within 5-10 working days.
YWHAZ, 14-3-3-zeta, HEL-S-3, HEL4, KCIP-1, YWHAD, HEL-S-93, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, POPCHAS
NP_001129171.1, NM_001135699.1
This product is for research use only.
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