Family main features
YWHAQ, also known as 14-3-3 protein theta, is a member of the 14-3-3 family of proteins, which are highly conserved across eukaryotic species and play critical roles in a variety of cellular processes. These proteins act as molecular scaffolds, facilitating protein-protein interactions by binding to phosphorylated serine/threonine residues on target proteins. YWHAQ is involved in numerous cellular functions, including signal transduction, cell cycle control, apoptosis, and response to stress. It is particularly significant in the brain, where it contributes to neuronal development, synaptic plasticity, and memory formation. Alterations in YWHAQ expression or function can lead to various diseases, including cancers and neurodegenerative disorders, making it an important target for therapeutic research.
The structure of YWHAQ, like other 14-3-3 proteins, is characterized by:
YWHAQ is one of the seven mammalian isoforms of the 14-3-3 protein family, which includes β, γ, ε, η, σ, τ, and ζ. Each isoform has unique as well as overlapping functions in different tissues and cellular contexts, contributing to the diversity of the 14-3-3 protein family's roles in cellular regulation.
YWHAQ is involved in several critical cellular functions:
Alterations in YWHAQ expression or function are linked to several diseases:
YWHAQ (14-3-3 protein theta) is a multifunctional adaptor protein involved in essential cellular processes, including signal transduction, cell cycle regulation, apoptosis, and stress response. Its conserved structure, featuring nine alpha helices and a phosphoserine/threonine-binding groove, enables it to interact with a wide range of phosphorylated target proteins. Dysregulation of YWHAQ is linked to various diseases, including cancer and neurodegenerative disorders, underscoring its importance in maintaining cellular homeostasis. Understanding the molecular mechanisms and interactions of YWHAQ can provide valuable insights into potential therapeutic targets for these diseases.
14-3-3 protein theta (YWHAQ)
YWHAQ, 14-3-3, 1C5, HS1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies, CLIA Kits) relacionados con YWHAQ - 14-3-3 protein theta
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 24 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | YWHAQ | abx516861 | Chicken 14-3-3 Protein Theta (YWHAQ) ELISA Kit | Chicken | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q5ZMD1 | RUO | ||
FineTest | YWHAQ | EH1591 | Human YWHAQ(14-3-3 protein theta) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.781-50ng/ml | 96T | P27348 | RUO | ||
Abbexa | YWHAQ | abx250882 | Human 14-3-3 Protein Theta (YWHAQ) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.78 ng/ml - 50 ng/ml | 687.5 | 96 tests | P27348 | RUO | |
Abbexa | YWHAQ | abx153545 | 14-3-3 Protein Theta (YWHAQ) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.13 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | YWHAQ | abx156960 | 14-3-3 Protein Theta (YWHAQ) ELISA Kit | Human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.06 ng/ml | 687.5 | 96 tests | RUO | |
Abbexa | YWHAQ | abx495787 | 14-3-3 Protein Theta (YWHAQ) CLIA Kit | Human | Serum, plasma, tissue homogenates and other biological fluids. | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.053 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | YWHAQ | abx516863 | Mouse 14-3-3 Protein Theta (YWHAQ) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.78 ng/ml - 50 ng/ml | 687.5 | 96 tests | P68254 | RUO | |
Abbexa | YWHAQ | abx516864 | Rat 14-3-3 Protein Theta (YWHAQ) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.156 ng/ml | 556.25 | 96 tests | P68255 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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Abbexa | YWHAQ | abx430901 | 14-3-3 Protein Theta (YWHAQ) Antibody | Human | Polyclonal | Goat | 14-3-3 Protein Theta (YWHAQ) | Unconjugated | P-ELISA, WB | 387.5 | 200 µl | RUO | ||
Abbexa | YWHAQ | abx320371 | 14-3-3 Protein Theta (YWHAQ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Theta (YWHAQ) | Unconjugated | ELISA, IHC | 237.5 | 50 µl | P27348 | RUO | |
Abbexa | YWHAQ | abx137294 | 14-3-3 Protein Theta (YWHAQ) Antibody | Human | Monoclonal | Mouse | 14-3-3 Protein Theta (YWHAQ) | Unconjugated | 225 | 5 µg | RUO | |||
Abbexa | YWHAQ | abx131164 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAq) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAq) | Unconjugated | WB, IHC, IF/ICC | 275 | 100 µl | RUO | ||
Abbexa | YWHAQ | abx322153 | 14-3-3 Protein Theta (YWHAQ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Theta (YWHAQ) | Unconjugated | ELISA, WB, IHC, IF/ICC | 237.5 | 50 µl | P27348 | RUO | |
Abbexa | YWHAQ | abx329559 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta Phospho-Ser232 (YWHAQ pS232) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta Phospho-Ser232 (YWHAQ pS232) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | P27348 | RUO | |
Abbexa | YWHAQ | abx329558 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAQ) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAQ) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | P27348 | RUO | |
Abbexa | YWHAQ | abx329392 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAQ) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAQ) | Unconjugated | ELISA, WB, IHC, IF/ICC | 187.5 | 50 µg | P27348 | RUO | |
Abbexa | YWHAQ | abx116387 | 14-3-3 Protein Theta (YWHAQ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Theta (YWHAQ) | Unconjugated | ELISA, WB, IF/ICC | 612.5 | 100 µl | P27348 | RUO | |
Abbexa | YWHAQ | abx214775 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAQ) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAQ) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P27348 | RUO | |
Abbexa | YWHAQ | abx013882 | 14-3-3 Protein Theta (YWHAQ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Theta (YWHAQ) | Unconjugated | ELISA, WB | 43.75 | 10 µg | P27348 | RUO | |
Abbexa | YWHAQ | abx002000 | 14-3-3 Protein Theta (YWHAQ) Antibody | Human | Polyclonal | Rabbit | 14-3-3 Protein Theta (YWHAQ) | Unconjugated | WB | 175 | 20 µl | P27348 | RUO | |
Abbexa | YWHAQ | abx241016 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAQ) Antibody | Human | Polyclonal | Rabbit | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAQ) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P27348 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | YWHAQ | abx650774 | Human Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAq) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | P27348 | RUO |
Abbexa | YWHAQ | abx073593 | Human 14-3-3 Protein Theta (YWHAQ) Protein | Human | Recombinant | E. coli | SDS-PAGE | 225 | 5 µg | P27348 | RUO | |
Abbexa | YWHAQ | abx655405 | Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Theta (YWHAq) Protein | Human, Mouse, Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 1800 | 1 mg | RUO |
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