Vascular Endothelial Growth Factor D / FIGF (VEGFD) Antibody (Biotin)
169€ (20 µg)
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935106861
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name
Vascular Endothelial Growth Factor D / FIGF (VEGFD) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx106066
tested applications
ELISA
Description
VEGFD Antibody (Biotin) is a Rabbit Polyclonal antibody against VEGFD conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Vascular Endothelial Growth Factor D / FIGF (VEGFD) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43915 |
| Gene ID | 2277 |
| OMIM | 300091 |
| Alias | FIGF,VEGF-D,c-Fos-induced growth factor |
| Background | Antibody anti-VEGFD |
| Status | RUO |
Descripción
VEGFD is a member of the vascular endothelial growth factor family that primarily promotes lymphangiogenesis and angiogenesis by binding to VEGF receptors VEGFR-2 and VEGFR-3 on endothelial cells VEGFD plays a key role in the development of lymphatic vessels during embryogenesis and in tissue repair by stimulating endothelial cell proliferation and migration It is also involved in cancer progression where VEGFD expression enhances tumor angiogenesis, lymphatic metastasis, and the spread of cancer cells Elevated levels of VEGFD have been observed in cancers such as breast cancer, melanoma, and lung cancer where it promotes the formation of new lymphatic vessels for tumor dissemination Its role in vascular biology makes VEGFD a target for therapies designed to inhibit lymphangiogenesis and reduce tumor metastasis
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