Vascular Endothelial Growth Factor D / FIGF (VEGFD) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Vascular Endothelial Growth Factor D / FIGF (VEGFD) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx025157
Tested Applications
ELISA, WB
Description
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Vascular Endothelial Growth Factor D / FIGF (VEGFD) Immunogen: Three KLH conjugated synthetic peptides corresponding to N-terminal, central, and C-terminal sequences of human VEGF4. |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/4000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | Calculated MW: 40.4 kDa |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43915 |
| NCBI Accession | NP_004460.1 |
| Alias | FIGF,VEGF-D,c-Fos-induced growth factor |
| Background | Antibody anti-VEGFD |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
VEGFD is a member of the vascular endothelial growth factor family that primarily promotes lymphangiogenesis and angiogenesis by binding to VEGF receptors VEGFR-2 and VEGFR-3 on endothelial cells VEGFD plays a key role in the development of lymphatic vessels during embryogenesis and in tissue repair by stimulating endothelial cell proliferation and migration It is also involved in cancer progression where VEGFD expression enhances tumor angiogenesis, lymphatic metastasis, and the spread of cancer cells Elevated levels of VEGFD have been observed in cancers such as breast cancer, melanoma, and lung cancer where it promotes the formation of new lymphatic vessels for tumor dissemination Its role in vascular biology makes VEGFD a target for therapies designed to inhibit lymphangiogenesis and reduce tumor metastasis
Productos relacionados
Vascular Endothelial Growth Factor D (FIGF) Antibody
FIGF Antibody is a Rabbit Polyclonal antibody against FIGF. The protein encoded by this gene is a member of the platelet…
Ver producto Vascular Endothelial Growth Factor D / FIGF (VEGFD) Antibody
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (P…
Ver producto
Vascular Endothelial Growth Factor D / FIGF (VEGFD) Antibody
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (P…
Ver producto