Uncharacterized AarF Domain-Containing Protein Kinase 1 (ADCK1) Antibody

357.5€ (100 µg)
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935106861
info@markelab.com
name
Uncharacterized AarF Domain-Containing Protein Kinase 1 (ADCK1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038093
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ADCK1 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Uncharacterized AarF Domain-Containing Protein Kinase 1 (ADCK1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by Protein A/G column chromatography. |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Lyophilized |
Tested Applications | ELISA, WB, IHC |
Buffer | Prior to lyophilization: 0.02% NaN3. |
Availability | Shipped within 7-15 working days. |
Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | MCP2 |
Background | Antibody anti-ADCK1 |
Status | RUO |
Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
aarF domain-containing kinase 1 (ADCK1) is part of the atypical kinase family characterized by the presence of an aarF domain, which is involved in coenzyme Q (CoQ) biosynthesis. ADCK1 is thought to function in mitochondrial processes, particularly in regulating the synthesis and stabilization of CoQ, an essential molecule in the electron transport chain for ATP production. While the specific physiological roles of ADCK1 remain under investigation, its expression in tissues with high energy demands suggests a key role in mitochondrial energy metabolism. Dysregulation of ADCK1 has been implicated in disorders related to mitochondrial dysfunction, oxidative stress, and metabolic imbalances. Emerging studies also suggest ADCK1 may participate in cellular signaling pathways linking energy metabolism and stress responses.
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