Uncharacterized AarF Domain-Containing Protein Kinase 1 (Adck1) Antibody

292.5€ (80 µl)
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935106861
info@markelab.com
name
Uncharacterized AarF Domain-Containing Protein Kinase 1 (Adck1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx028173
tested applications
ELISA, WB
Description
The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Uncharacterized AarF Domain-Containing Protein Kinase 1 (Adck1) |
Host | Rabbit |
Reactivity | Mouse |
Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Size 1 | 80 µl |
Size 2 | 400 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9D0L4 |
Alias | MCP2 |
Background | Antibody anti-ADCK1 |
Status | RUO |
Descripción
aarF domain-containing kinase 1 (ADCK1) is part of the atypical kinase family characterized by the presence of an aarF domain, which is involved in coenzyme Q (CoQ) biosynthesis. ADCK1 is thought to function in mitochondrial processes, particularly in regulating the synthesis and stabilization of CoQ, an essential molecule in the electron transport chain for ATP production. While the specific physiological roles of ADCK1 remain under investigation, its expression in tissues with high energy demands suggests a key role in mitochondrial energy metabolism. Dysregulation of ADCK1 has been implicated in disorders related to mitochondrial dysfunction, oxidative stress, and metabolic imbalances. Emerging studies also suggest ADCK1 may participate in cellular signaling pathways linking energy metabolism and stress responses.
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