Uncharacterized AarF Domain-Containing Protein Kinase 1 (ADCK1) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Uncharacterized AarF Domain-Containing Protein Kinase 1 (ADCK1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx013678
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against ADCK1 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Uncharacterized AarF Domain-Containing Protein Kinase 1 (ADCK1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q86TW2 |
| Alias | MCP2 |
| Background | Antibody anti-ADCK1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
aarF domain-containing kinase 1 (ADCK1) is part of the atypical kinase family characterized by the presence of an aarF domain, which is involved in coenzyme Q (CoQ) biosynthesis. ADCK1 is thought to function in mitochondrial processes, particularly in regulating the synthesis and stabilization of CoQ, an essential molecule in the electron transport chain for ATP production. While the specific physiological roles of ADCK1 remain under investigation, its expression in tissues with high energy demands suggests a key role in mitochondrial energy metabolism. Dysregulation of ADCK1 has been implicated in disorders related to mitochondrial dysfunction, oxidative stress, and metabolic imbalances. Emerging studies also suggest ADCK1 may participate in cellular signaling pathways linking energy metabolism and stress responses.
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