Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Antibody
357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx038021
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the TNFRSF21 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Immunogen: A peptide corresponding to N-terminal region of human TNFRSF21 protein. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 72 kDa |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Tumor necrosis factor receptor superfamily member 21,DR6,CD358,BM-018,Death receptor 6 |
| Background | Antibody anti-TNFRSF21 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
TNF receptor superfamily member 21 (TNFRSF21), also known as death receptor 6 (DR6), is a member of the tumor necrosis factor receptor (TNFR) superfamily. Like other TNFR members, TNFRSF21 is involved in processes that modulate immune responses, cell death, and survival pathways. This receptor is particularly involved in apoptosis, immune cell regulation, and central nervous system functions. TNFRSF21/DR6 is expressed in a range of tissues but is predominantly found in lymphoid organs, nervous system cells, and tissues associated with inflammatory processes. TNFRSF21 plays a significant role in neuroinflammation and neurodegeneration, as well as in the regulation of immune responses. It is a type I transmembrane protein that acts as a receptor for ligands like tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and amyloid precursor protein (APP)-derived peptides. Due to its involvement in cell apoptosis, particularly in neural cells, TNFRSF21 has garnered interest for its potential therapeutic applications in neurodegenerative diseases such as Alzheimer’s disease. Additionally, its function in immune cell regulation places it as a candidate target in autoimmune diseases and certain cancers.
Productos relacionados
Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Antibody
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate N…
Ver producto Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Antibody
Rabbit Polyclonal against the TNFRSF21 protein.…
Ver producto
Mouse Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Protein
Mouse Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) is a recombinant Mouse protein expressed in E. co…
Ver producto