Thrombomodulin (THBD) Antibody

Este producto es parte de THBD - thrombomodulin
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52€ (10 µg)

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935106861
info@markelab.com
name
Thrombomodulin (THBD) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014946
tested applications
ELISA, WB

Description

Rabbit polyclonal antibody against THBD protein. Immunogen region is C-terminal.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Thrombomodulin (THBD)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/500 - 1/3000, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 1
10 µg
Size 2
100 µg
Size 3
200 µg
Size 4
300 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P07204
Alias
Fetomodulin, TM,THRM,AHUS6,BDCA3,CD141,BDCA-3,THPH12
Background
Antibody anti-THBD
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

Thrombomodulin (THBD) is an endothelial cell membrane protein with critical anticoagulant properties. It serves as a cofactor in thrombin-mediated activation of protein C, which plays a significant role in regulating blood coagulation and maintaining vascular integrity. Beyond hemostasis, thrombomodulin is involved in numerous physiological functions, including inflammation control, cell proliferation, and protection against oxidative stress. Its expression is most prominent on endothelial cells lining the blood vessels but can also be found in other cell types, such as epithelial and some immune cells. Because of its crucial role in anticoagulation and endothelial function, thrombomodulin dysregulation is associated with various vascular, inflammatory, and coagulation disorders, as well as certain cancer types.

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