Mouse Thrombomodulin (THBD) Protein
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935106861
info@markelab.com
Precio
3224€ (1 mg)
Protein THBD
proveedor
Abbexareference
abx069272Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Thrombomodulin (TM) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
Thrombomodulin (THBD) is an endothelial cell membrane protein with critical anticoagulant properties. It serves as a cofactor in thrombin-mediated activation of protein C, which plays a significant role in regulating blood coagulation and maintaining vascular integrity. Beyond hemostasis, thrombomodulin is involved in numerous physiological functions, including inflammation control, cell proliferation, and protection against oxidative stress. Its expression is most prominent on endothelial cells lining the blood vessels but can also be found in other cell types, such as epithelial and some immune cells. Because of its crucial role in anticoagulation and endothelial function, thrombomodulin dysregulation is associated with various vascular, inflammatory, and coagulation disorders, as well as certain cancer types.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Thrombomodulin (THBD)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
1 mg
size 2
5 mg
observerd MW
Molecular Weight: Calculated MW: 16.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val31-Phe167 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
THBD
dry ice
No
availability
Shipped within 1-2 months.
alias
Fetomodulin, TM,THRM,AHUS6,BDCA3,CD141,BDCA-3,THPH12
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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
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