Taste Receptor Type 2 Member 49 (TAS2R49) Antibody

Background

TAS2R20 is a member of the TAS2R family of receptors, responsible for the detection of bitter compounds. These receptors are primarily expressed in the taste cells of the tongue, where they are activated by a variety of bitter substances. When TAS2R20 is stimulated by its ligands, it activates intracellular signaling pathways, leading to the sensation of bitterness. This receptor plays a protective role in the body’s response to potentially toxic substances, as many bitter compounds are associated with harmful chemicals. Genetic variations in TAS2R20 can affect an individual's sensitivity to bitterness, contributing to differences in taste preferences and food choices. Understanding TAS2R20's role in bitter taste detection can provide insights into how humans perceive bitter flavors and how this perception influences dietary habits.