Taste 2 Receptor Member 43 (TAS2R43) Antibody

Background

TAS2R43 is part of the bitter taste receptor family, specifically responsible for detecting bitter compounds. This receptor is expressed in taste cells on the tongue, where it responds to various bitter molecules. Upon binding with bitter ligands, TAS2R43 activates intracellular signaling pathways that lead to the perception of bitterness. This process is part of the body's protective mechanism, alerting the individual to potentially toxic or harmful substances commonly associated with bitter tastes. The sensitivity of TAS2R43 to specific bitter compounds can vary depending on genetic factors, contributing to individual differences in taste preferences. TAS2R43 is important for understanding how the body detects bitter substances, influencing dietary choices and food aversions. Studying this receptor may offer insights into food product design, particularly for reducing bitterness or understanding the genetic basis of food preferences.