Syndecan 2 (SDC2) Antibody (Biotin)
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Description
Heparan Sulfate Proteoglycan (HSPG) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Heparan Sulfate Proteoglycan (HSPG).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Syndecan 2 (SDC2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 200 µl |
| Size 2 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Syndecan-2,HSPG,CD362,HSPG1,SYND2,Fibroglycan,Heparan sulfate proteoglycan core protein |
| Background | Antibody anti-SDC2 |
| Status | RUO |
Descripción
Syndecan-2 (SDC2) is a transmembrane heparan sulfate proteoglycan that is part of the syndecan family, which consists of four members (SDC1-SDC4). Syndecans are integral to cellular processes involved in adhesion, migration, and signal transduction. SDC2, specifically, plays a role in modulating cell-extracellular matrix (ECM) interactions, making it crucial for processes such as angiogenesis, inflammation, and wound healing. This proteoglycan is abundantly expressed in tissues such as endothelial cells, fibroblasts, and some types of epithelial cells and neurons, especially during development. SDC2's function in facilitating cell-to-cell and cell-to-matrix interactions underscores its role in maintaining tissue structure and facilitating responses to external stimuli.
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Syndecan 2 (SDC2) Antibody
SDC2 Antibody is a Rabbit Polyclonal antibody against SDC2. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008].
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