Syndecan 2 (SDC2) Antibody

Name: Syndecan 2 (SDC2) Antibody
Brand: Abbexa
SKU: abx001497
Price: 195 EUR
Availability: OnlineOnly

Este producto es parte de SDC2 - syndecan 2

Pida mas información

935106861

info@markelab.com

Precio

195€ (20 µl)

Antibody anti-SDC2

proveedor

Abbexa

reference

abx001497

Tested Applications

ELISA, WB, IHC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

SDC2 Antibody is a Rabbit Polyclonal antibody against SDC2. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008].

Background

Syndecan-2 (SDC2) is a transmembrane heparan sulfate proteoglycan that is part of the syndecan family, which consists of four members (SDC1-SDC4). Syndecans are integral to cellular processes involved in adhesion, migration, and signal transduction. SDC2, specifically, plays a role in modulating cell-extracellular matrix (ECM) interactions, making it crucial for processes such as angiogenesis, inflammation, and wound healing. This proteoglycan is abundantly expressed in tissues such as endothelial cells, fibroblasts, and some types of epithelial cells and neurons, especially during development. SDC2's function in facilitating cell-to-cell and cell-to-matrix interactions underscores its role in maintaining tissue structure and facilitating responses to external stimuli.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Syndecan 2 (SDC2)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC

purification

Purified by affinity chromatography.

recommended dilution

ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

size 1

20 µl

size 2

100 µl

size 3

2 × 100 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

SDC2

dry ice

availability

Shipped within 5-10 working days.

alias

Syndecan-2,HSPG,CD362,HSPG1,SYND2,Fibroglycan,Heparan sulfate proteoglycan core protein

uniprot id

https://www.uniprot.org/uniprotkb/P34741

gene id

https://www.ncbi.nlm.nih.gov/gene/6383

NCBI accession

NP_002989.2

note

Concentration: 1.21 mg/ml -

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proveedor

FineTest

reference

EM0754

reactivity

mouse

status

RUO

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