Human Syndecan 2 (SDC2) Protein

Este producto es parte de SDC2 - syndecan 2
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208€ (10 µg)

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935106861
info@markelab.com
name
Human Syndecan 2 (SDC2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067053
tested applications
WB, SDS-PAGE

Description

Heparan Sulfate Proteoglycan (HSPG) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Syndecan 2 (SDC2)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 15.2 kDa
Observed MW (SDS-PAGE): 23 kDa

Possible reasons why the actual band size differs from the predicted band size:
1. Splice variants. Alternative splicing may create different sized proteins from the same gene.
2. Relative charge. The composition of amino acids may affect the charge of the protein.
3. Post-translational modification. Phosphorylation, glycoslyation, methylation etc. may affect the band size.
4. Post-translational cleavage. Many proteins are synthesised as pro-proteins, and then cleaved to give the active form.
5. Polymerisation of the target protein. Dimerisation, multimerisation etc. will increase the band size observed.
Concentration: Prior to lyophilization: 150 µg/ml
Sequence Fragment: Glu19-Glu144
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P34741
Alias
Syndecan-2,HSPG,CD362,HSPG1,SYND2,Fibroglycan,Heparan sulfate proteoglycan core protein
Background
Protein SDC2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Syndecan-2 (SDC2) is a transmembrane heparan sulfate proteoglycan that is part of the syndecan family, which consists of four members (SDC1-SDC4). Syndecans are integral to cellular processes involved in adhesion, migration, and signal transduction. SDC2, specifically, plays a role in modulating cell-extracellular matrix (ECM) interactions, making it crucial for processes such as angiogenesis, inflammation, and wound healing. This proteoglycan is abundantly expressed in tissues such as endothelial cells, fibroblasts, and some types of epithelial cells and neurons, especially during development. SDC2's function in facilitating cell-to-cell and cell-to-matrix interactions underscores its role in maintaining tissue structure and facilitating responses to external stimuli.

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