RNA-Binding Protein T-Star (KHDRBS3) Antibody
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Description
KHDRBS3 Antibody is a Rabbit Polyclonal antibody against KHDRBS3.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RNA-Binding Protein T-Star (KHDRBS3) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75525 |
| Gene ID | 10656 |
| NCBI Accession | NP_006549.1 |
| Alias | Etle, SALP, SLM-2, SLM2, T-STAR, TSTAR, etoile,RNA-binding protein T-Star |
| Background | Antibody anti-KHDRBS3 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
KHDRBS3, also known as T-STAR (testis-signal transduction and activation of RNA), is a member of the Sam68 family of KH-domain RNA-binding proteins. It regulates alternative splicing, RNA transport, and translation, linking RNA processing to cellular signaling pathways. KHDRBS3 is highly expressed in the testis and brain, where it regulates spermatogenesis, synaptic plasticity, and germ cell development. It interacts with signaling proteins, including tyrosine kinases, and is involved in cell cycle control, meiosis, and differentiation. Dysregulation of KHDRBS3 is associated with infertility and neurological disorders due to defects in RNA metabolism and cellular differentiation. Knockout studies show impaired germ cell development and reduced neuronal plasticity, highlighting its critical role in tissue-specific gene expression and RNA regulation.
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