Retinoic Acid Receptor RXR-Beta (RXRB) Antibody

Este producto es parte de RXR - retinoid X receptor
Retinoic Acid Receptor RXR-Beta (RXRB) Antibody
377€ (100 µg)

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Name
Retinoic Acid Receptor RXR-Beta (RXRB) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx237544
Tested Applications
ELISA, WB, IP

Description

RXRB Antibody is a Rabbit Polyclonal against RXRB.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Retinoic Acid Receptor RXR-Beta (RXRB)
Immunogen: retinoid X receptor, beta
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: 2 mg/ml
Recommended Dilution
WB: 1/500 - 1/2000, IP: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Observed MW: 57 kDa
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by immunogen affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IP
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P28702
Gene ID
6257
NCBI Accession
NP_001257330.1, NM_001270401.1, NP_068811.1, NM_021976.4
OMIM
180246
Alias
NR2B2,DAUDI6,RCoR-1,RXRbeta,H-2RIIBP,RXR-beta,Retinoic acid receptor RXR-beta,Retinoid X receptor beta,Nuclear receptor subfamily 2 group B member 2
Background
Antibody anti-RXRB
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Retinoid X receptor beta (RXRB) is another member of the RXR family, with a role in mediating the effects of retinoids and regulating gene expression RXRB forms heterodimers with RXRA and other nuclear receptors, influencing various physiological processes including lipid metabolism, cellular differentiation, and inflammation It is widely expressed in tissues such as the liver, brain, and heart, where it regulates the expression of genes involved in fat metabolism, cholesterol homeostasis, and glucose metabolism RXRB also plays an important role in the immune system, where it helps modulate the activity of immune cells and inflammatory responses Dysregulation of RXRB has been implicated in metabolic diseases, such as obesity and type 2 diabetes, as well as cardiovascular diseases where altered lipid metabolism and inflammation contribute to disease progression RXRB represents a potential therapeutic target for the treatment of metabolic disorders, inflammatory diseases, and cancer

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