anti- RXRB antibody
Pida mas información
935106861
info@markelab.com
Precio
Precio a consultar
Antibody anti-RXRB
proveedor
FineTestreference
FNab07544Tested Applications
ELISA, WB, IPreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements(RARE).
Background
Retinoid X receptor beta (RXRB) is another member of the RXR family, with a role in mediating the effects of retinoids and regulating gene expression RXRB forms heterodimers with RXRA and other nuclear receptors, influencing various physiological processes including lipid metabolism, cellular differentiation, and inflammation It is widely expressed in tissues such as the liver, brain, and heart, where it regulates the expression of genes involved in fat metabolism, cholesterol homeostasis, and glucose metabolism RXRB also plays an important role in the immune system, where it helps modulate the activity of immune cells and inflammatory responses Dysregulation of RXRB has been implicated in metabolic diseases, such as obesity and type 2 diabetes, as well as cardiovascular diseases where altered lipid metabolism and inflammation contribute to disease progression RXRB represents a potential therapeutic target for the treatment of metabolic disorders, inflammatory diseases, and cancer
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
retinoid X receptor, beta
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IP
observerd MW
57 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
RXRB
alias
NR2B2,DAUDI6,RCoR-1,RXRbeta,H-2RIIBP,RXR-beta,Retinoic acid receptor RXR-beta,Retinoid X receptor beta,Nuclear receptor subfamily 2 group B member 2
uniprot id
note
This product is for research use only.
Quizá le pueda interesar
Human RXRB(Retinoic acid receptor RXR-beta) ELISA Kit
proveedor
FineTestreference
EH1199reactivity
humanstatus
RUOPrecio a consultar
Ver másMouse Rxrb(Retinoic acid receptor RXR-beta) ELISA Kit
proveedor
FineTestreference
EM0505reactivity
mousestatus
RUOPrecio a consultar
Ver másanti- RXRB antibody
proveedor
FineTestreference
FNab07544Tested Applications
ELISA, WB, IPreactivity
human,mouse,ratstatus
RUOclonality
polyclonalReceptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response t...
Precio a consultar
Ver más