anti- RXRB antibody

Este producto es parte de RXR - retinoid X receptor
anti- RXRB antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-RXRB

proveedor

FineTest

reference

FNab07544

Tested Applications

ELISA, WB, IP

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements(RARE).


Background

Retinoid X receptor beta (RXRB) is another member of the RXR family, with a role in mediating the effects of retinoids and regulating gene expression RXRB forms heterodimers with RXRA and other nuclear receptors, influencing various physiological processes including lipid metabolism, cellular differentiation, and inflammation It is widely expressed in tissues such as the liver, brain, and heart, where it regulates the expression of genes involved in fat metabolism, cholesterol homeostasis, and glucose metabolism RXRB also plays an important role in the immune system, where it helps modulate the activity of immune cells and inflammatory responses Dysregulation of RXRB has been implicated in metabolic diseases, such as obesity and type 2 diabetes, as well as cardiovascular diseases where altered lipid metabolism and inflammation contribute to disease progression RXRB represents a potential therapeutic target for the treatment of metabolic disorders, inflammatory diseases, and cancer

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

retinoid X receptor, beta


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IP


observerd MW

57 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500-1:2000; IP: 1:200-1:2000


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

RXRB


alias

NR2B2,DAUDI6,RCoR-1,RXRbeta,H-2RIIBP,RXR-beta,Retinoic acid receptor RXR-beta,Retinoid X receptor beta,Nuclear receptor subfamily 2 group B member 2


note

This product is for research use only.


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Tested Applications

ELISA, WB, IP

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human,mouse,rat

status

RUO

clonality

polyclonal

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response t...

Precio a consultar

Ver más