Recombinant Human CORO1C
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935106861
info@markelab.com
name
Recombinant Human CORO1C
category
Proteins and Peptides
provider
FineTest
reference
P8289
tested applications
Western Blot, ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | 1-207 |
| Host | E.Coli |
| Origin | Human |
| Observed MW | 43.6 kDa |
| Expression | Recombinant |
| Purity | Greater than 95% by SDS-PAGE gel analyses |
| Purification | N-terminal His-IF2DI Tag |
| Size 1 | 50μg |
| Size 2 | 200μg |
| Size 3 | 1mg |
| Form | Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.06% proclin, pH7.4 |
| Tested Applications | Western Blot, ELISA |
| Buffer | Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 200 μg/ml in Reconstitute with Sterile distilled water |
| Availability | 3-4 weeks |
| Storage | -20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution |
| UniProt ID | Q9ULV4 |
| Alias | HCRNN4,Coronin-3,Coronin-1C,CRN2,CRNN4 |
| Background | Proteins CORO1C |
| Status | RUO |
| Note | This product is for research use only. |
Coronin 1C (CORO1C) is another member of the coronin protein family with a role in regulating actin filament dynamics. Like CORO1A and CORO1B, CORO1C plays a crucial role in cellular processes such as actin-based movement, endocytosis, and cytokinesis. However, CORO1C is particularly important in the regulation of the immune system, where it modulates the signaling pathways of immune cells, including T cells, and contributes to the response to inflammation. It is also involved in maintaining the structural integrity of immune synapses, which are crucial for the communication between immune cells. Similar to the other coronins, CORO1C's dysregulation can impair immune function and has been associated with conditions that affect immune responses. Understanding the role of CORO1C in immune cell signaling and actin dynamics is critical for advancing therapeutic strategies targeting immune-related diseases.
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