Coronin 1C (CORO1C) Antibody
357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Coronin 1C (CORO1C) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx036112
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the CORO1C protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Coronin 1C (CORO1C) Immunogen: Recombinant fragment corresponding to 269-471 AA of human CORO1C. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 53 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | HCRNN4,Coronin-3,Coronin-1C,CRN2,CRNN4 |
| Background | Antibody anti-CORO1C |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Coronin 1C (CORO1C) is another member of the coronin protein family with a role in regulating actin filament dynamics. Like CORO1A and CORO1B, CORO1C plays a crucial role in cellular processes such as actin-based movement, endocytosis, and cytokinesis. However, CORO1C is particularly important in the regulation of the immune system, where it modulates the signaling pathways of immune cells, including T cells, and contributes to the response to inflammation. It is also involved in maintaining the structural integrity of immune synapses, which are crucial for the communication between immune cells. Similar to the other coronins, CORO1C's dysregulation can impair immune function and has been associated with conditions that affect immune responses. Understanding the role of CORO1C in immune cell signaling and actin dynamics is critical for advancing therapeutic strategies targeting immune-related diseases.
Productos relacionados
Coronin 1C (CORO1C) Antibody
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately …
Ver producto Coronin 1C (CORO1C) Antibody
Coronin, Actin Binding Protein, 1C Polyclonal Antibody is a Rabbit Polyclonal antibody against Coronin, Actin Binding Pr…
Ver producto