Rat Vasoactive intestinal polypeptide receptor 2 (VIPR2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for VIPR2
proveedor
Abbexareference
abx556226Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Vasoactive intestinal polypeptide receptor 2 (VIPR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Vasoactive intestinal polypeptide receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
VIPR2 is a G protein-coupled receptor activated by vasoactive intestinal peptide (VIP), a neuropeptide that plays a central role in regulating smooth muscle relaxation, vasodilation, and neurotransmission. VIPR2 primarily couples to Gs proteins, activating adenylate cyclase, which increases intracellular cAMP levels and leads to the relaxation of smooth muscle cells and dilation of blood vessels. It is expressed in the smooth muscle of the gastrointestinal tract, heart, lungs, and brain. VIPR2 has significant roles in regulating gastrointestinal motility, vascular tone, and immune cell activity. Dysregulation of VIPR2 signaling is implicated in diseases such as asthma, irritable bowel syndrome (IBS), and inflammatory disorders. VIPR2 antagonists are being studied for their potential in treating these diseases, as they could help reduce excessive smooth muscle contraction and inflammation.
Características del producto
category
ELISA Kits
immunogen target
Vasoactive intestinal polypeptide receptor 2 (VIPR2)
reactivity
Rat
test range
0.625 ng/ml - 40 ng/ml
sensitivity
< 0.21 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
VIPR2,VPAC,Helodermin-preferring VIP recepto,Pituitary adenylate cyclase-activating polypeptide type III recepto,PACAP type III recepto,PACAP-R-,PACAP-R,VIP2R
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
VIPR2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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