Human Vasoactive intestinal polypeptide receptor 2 (VIPR2) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Vasoactive intestinal polypeptide receptor 2 (VIPR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx251072
tested applications
ELISA
Description
Human Vasoactive intestinal polypeptide receptor 2 (VIPR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Vasoactive intestinal polypeptide receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Vasoactive intestinal polypeptide receptor 2 (VIPR2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P41587 |
| Alias | VIPR2,VPAC,Helodermin-preferring VIP recepto,Pituitary adenylate cyclase-activating polypeptide type III recepto,PACAP type III recepto,PACAP-R-,PACAP-R,VIP2R |
| Background | Elisa kits for VIPR2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
VIPR2 is a G protein-coupled receptor activated by vasoactive intestinal peptide (VIP), a neuropeptide that plays a central role in regulating smooth muscle relaxation, vasodilation, and neurotransmission. VIPR2 primarily couples to Gs proteins, activating adenylate cyclase, which increases intracellular cAMP levels and leads to the relaxation of smooth muscle cells and dilation of blood vessels. It is expressed in the smooth muscle of the gastrointestinal tract, heart, lungs, and brain. VIPR2 has significant roles in regulating gastrointestinal motility, vascular tone, and immune cell activity. Dysregulation of VIPR2 signaling is implicated in diseases such as asthma, irritable bowel syndrome (IBS), and inflammatory disorders. VIPR2 antagonists are being studied for their potential in treating these diseases, as they could help reduce excessive smooth muscle contraction and inflammation.
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Vasoactive Intestinal Polypeptide Receptor 2 (VIPR2) Antibody
Vasoactive intestinal peptide (VIP; MIM 192320) and pituitary adenylate cyclase activating polypeptide (PACAP; MIM 102980) are homologous peptides that function as neurotransmitters and neuroendocrine hormones. While the receptors for VIP and PACAP share homology, they differ in their substrate specificities and expression patterns. See VIPR1 (MIM 192321) and ADCYAP1R1 (MIM 102981).
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