Rat Syndecan 2 (SDC2) Protein
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Description
Rat Heparan Sulfate Proteoglycan (HSPG) Protein is a Recombinant Rat protein expressed in E. coli.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Syndecan 2 (SDC2) |
| Host | E. coli |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 1-2 months. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Syndecan-2,HSPG,CD362,HSPG1,SYND2,Fibroglycan,Heparan sulfate proteoglycan core protein |
| Background | Protein SDC2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Syndecan-2 (SDC2) is a transmembrane heparan sulfate proteoglycan that is part of the syndecan family, which consists of four members (SDC1-SDC4). Syndecans are integral to cellular processes involved in adhesion, migration, and signal transduction. SDC2, specifically, plays a role in modulating cell-extracellular matrix (ECM) interactions, making it crucial for processes such as angiogenesis, inflammation, and wound healing. This proteoglycan is abundantly expressed in tissues such as endothelial cells, fibroblasts, and some types of epithelial cells and neurons, especially during development. SDC2's function in facilitating cell-to-cell and cell-to-matrix interactions underscores its role in maintaining tissue structure and facilitating responses to external stimuli.
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SDC2 Antibody is a Rabbit Polyclonal antibody against SDC2. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008].
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