Rat MAS Related GPR Family Member X1 (MRGPRX1) ELISA Kit

Este producto es parte de MRGPRX - MAS related GPR family member X
Rat MAS Related GPR Family Member X1 (MRGPRX1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for MRGPRX1

proveedor

Abbexa

reference

abx533643

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat MAS Related GPR Family Member X1 (MRGPRX1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Mas-related G-protein coupled receptor member X1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

MRGPRX1 is a member of the MAS-related G protein-coupled receptor (GPCR) family, which is involved in various sensory and immune functions. It is primarily expressed in sensory neurons, particularly in the skin and mucosal tissues. MRGPRX1 plays a critical role in mediating itch sensations and allergic responses. It is activated by specific neuropeptides, such as substance P and various mast cell mediators, which lead to the activation of intracellular signaling pathways. Upon activation, MRGPRX1 typically couples to G proteins, initiating the release of calcium ions and the production of other intracellular signals. This process contributes to inflammatory responses and the sensation of itching. Dysregulation of MRGPRX1 has been implicated in conditions such as chronic urticaria (hives) and other allergic skin disorders. As such, MRGPRX1 is a potential target for novel therapies aimed at controlling itch and allergic inflammation.

Características del producto

category

ELISA Kits


immunogen target

MAS Related GPR Family Member X1 (MRGPRX1)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

MRGPRX1,Mrgc,Mrgprb2,Mrgprc,Mrgprc11,MRGX1,Sensory neuron-specific G-protein coupled receptor 4,SNSR4,GPCR, MGRG2, MRGX1, SNSR4


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

MRGPRX1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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