MAS Related GPR Family Member X1 (MRGPRX1) Antibody
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
MAS Related GPR Family Member X1 (MRGPRX1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx211003
tested applications
ELISA, IHC
Description
MRGPRX1 Antibody is a Rabbit Polyclonal against MRGPRX1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | MAS Related GPR Family Member X1 (MRGPRX1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/2000 - 1/5000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96LB2 |
| Gene ID | 259249 |
| Alias | MRGPRX1,Mrgc,Mrgprb2,Mrgprc,Mrgprc11,MRGX1,Sensory neuron-specific G-protein coupled receptor 4,SNSR4,GPCR, MGRG2, MRGX1, SNSR4 |
| Background | Antibody anti-MRGPRX1 |
| Status | RUO |
Descripción
MRGPRX1 is a member of the MAS-related G protein-coupled receptor (GPCR) family, which is involved in various sensory and immune functions. It is primarily expressed in sensory neurons, particularly in the skin and mucosal tissues. MRGPRX1 plays a critical role in mediating itch sensations and allergic responses. It is activated by specific neuropeptides, such as substance P and various mast cell mediators, which lead to the activation of intracellular signaling pathways. Upon activation, MRGPRX1 typically couples to G proteins, initiating the release of calcium ions and the production of other intracellular signals. This process contributes to inflammatory responses and the sensation of itching. Dysregulation of MRGPRX1 has been implicated in conditions such as chronic urticaria (hives) and other allergic skin disorders. As such, MRGPRX1 is a potential target for novel therapies aimed at controlling itch and allergic inflammation.
Related Products
MAS Related GPR Family Member X1 (MRGPRX1) Antibody
MRGPRX1 Antibody is a Rabbit Polyclonal against MRGPRX1.
Ver ProductoMAS Related GPR Family Member X1 (MRGPRX1) Antibody
MRGPRX1 Antibody is a Rabbit Polyclonal against MRGPRX1.
Ver ProductoMAS Related GPR Family Member X1 (MRGPRX1) Antibody
MRGPRX1 Antibody is a Rabbit Polyclonal against MRGPRX1.
Ver Producto