Rat Fructose-Bisphosphate Aldolase A (ALDOA) Protein

Este producto es parte de ALDOA - Fructose-Bisphosphate Aldolase A
Rat Fructose-Bisphosphate Aldolase A (ALDOA) Protein

Pida mas información

935106861

info@markelab.com

Precio

1872€ (1 mg)

Protein ALDOA

proveedor

Abbexa

reference

abx652451

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rat Aldolase A, Fructose Bisphosphate (ALDOA) Protein is a Recombinant Rat protein expressed in E. coli.


Background

ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate during glycolysis. It is widely expressed, particularly in muscle tissues and the brain, where it plays a crucial role in energy metabolism and ATP production. ALDOA is vital for providing energy to rapidly proliferating cells and tissues with high metabolic demands. Dysregulation of ALDOA has been associated with cancer progression, as elevated glycolytic activity (Warburg effect) fuels tumor growth. Mutations in ALDOA cause glycogen storage disease type XII, characterized by hemolytic anemia and muscle weakness due to impaired glycolytic flux. Its role in energy metabolism underscores its importance in cellular homeostasis, growth, and disease.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Fructose-Bisphosphate Aldolase A (ALDOA)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

1 mg


size 2

5 mg


observerd MW

Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Please enquire. Tag: N-terminal His tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ALDOA


dry ice

No


availability

Shipped within 1-2 months.


alias

ALDOA,ALDA


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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