Rat Anterior Gradient Protein 2 (AGR2) Protein

Este producto es parte de AGR - Anterior gradient 2, protein disulphide isomerase family member
Rat Anterior Gradient Protein 2 (AGR2) Protein

Pida mas información

935106861

info@markelab.com

Precio

208€ (10 µg)

Protein AGR2

proveedor

Abbexa

reference

abx065387

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Anterior Gradient Protein 2 (AGR2) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

AGR2 is a protein involved in the endoplasmic reticulum (ER) stress response and functions as a protein disulfide isomerase (PDI), facilitating the proper folding of secreted and membrane proteins. It is primarily expressed in secretory tissues such as the gastrointestinal tract, lungs, and prostate, where it maintains ER homeostasis by catalyzing the formation of disulfide bonds in proteins. AGR2 also plays a role in cell adhesion and migration, partly through its interaction with mucins like MUC1 and MUC2. Overexpression of AGR2 is frequently observed in cancers, including breast, pancreatic, and prostate cancers, where it contributes to tumor progression, chemoresistance, and metastasis by promoting cell survival under stress conditions

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Anterior Gradient Protein 2 (AGR2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 23.5 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Lys21-Leu175 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

AGR2


dry ice

No


availability

Shipped within 5-12 working days.


alias

AG-2,AG2,GOB-4,HAG-2,HEL-S-116,HPC8


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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