Rat Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501472
tested applications
ELISA
Description
Rat Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Aldehyde dehydrogenase family 1 member L1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P28037 |
| Alias | ALDH1L1,FTHFD |
| Background | Elisa kits for ALDH1L1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ALDH1L1, also known as 10-formyltetrahydrofolate dehydrogenase, is a cytosolic enzyme involved in folate metabolism, where it catalyzes the conversion of 10-formyltetrahydrofolate to tetrahydrofolate, a key process in one-carbon metabolism. This enzyme plays a significant role in nucleotide biosynthesis, DNA methylation, and cellular proliferation by regulating the folate cycle and one-carbon pools. ALDH1L1 is highly expressed in the liver and brain, where it supports metabolic processes and detoxification. It functions as a tumor suppressor, as its loss or downregulation is associated with various cancers, including liver, breast, and lung cancers, due to impaired folate metabolism and increased cellular proliferation. ALDH1L1 also contributes to cellular detoxification by reducing reactive aldehydes and maintaining redox balance. Emerging studies highlight its potential as a biomarker for cancer prognosis and as a therapeutic target for restoring normal folate metabolism in tumor cells.
Related Products
ALDH1L1 antibody
Ver Producto
Recombinant Human ALDH1L1
Ver Producto
Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) Antibody
ALDH1L1 Antibody is a Rabbit Polyclonal Antibody against ALDH1L1.
Ver Producto