P2Y Purinoceptor 2 (P2RY2) Antibody
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
P2Y Purinoceptor 2 (P2RY2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx210413
Tested Applications
ELISA, WB
Description
P2RY2 Antibody is a Rabbit Polyclonal against P2RY2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: P2Y Purinoceptor 2 (P2RY2) Immunogen: Synthetic peptide of human P2RY2. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/2000 - 1/10000, WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P41231 |
| Gene ID | 5029 |
| Alias | P2RY2,ATP receptor,P2U purinoceptor 1,P2Y ATP receptor 2,P2Y purinoceptor 2,purinergic receptor P2Y,HP2U, P2RU1, P2U, P2U1, P2UR, P2Y2 |
| Background | Antibody anti-P2RY2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
P2RY2 is a G protein-coupled receptor activated by ATP and UTP, serving as a key regulator of cellular responses to extracellular nucleotides. It is widely expressed in epithelial cells, endothelial cells, and immune cells, where it couples to Gq proteins, activating phospholipase C (PLC), increasing intracellular calcium, and modulating cytoskeletal dynamics and ion transport. P2RY2 plays a critical role in regulating inflammation, wound healing, and fluid secretion. In the respiratory tract, P2RY2 mediates mucus secretion and airway hydration, making it a therapeutic target for cystic fibrosis and chronic obstructive pulmonary disease (COPD). In addition, P2RY2 is involved in vascular remodeling, angiogenesis, and immune cell recruitment during tissue repair and inflammation. Dysregulation of P2RY2 contributes to inflammatory diseases, cardiovascular dysfunction, and fibrosis. P2RY2 agonists and antagonists are being explored for their potential in treating respiratory disorders, wound healing, and chronic inflammatory conditions.
Productos relacionados
P2Y Purinoceptor 2 (P2RY2) Antibody
P2RY2 Antibody is a Rabbit Polyclonal antibody against P2RY2. The product of this gene belongs to the family of P2 recep…
Ver producto
P2Y Purinoceptor 2 (P2RY2) Antibody
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes…
Ver producto P2Y Purinoceptor 2 (P2RY2) Antibody
P2RY2 Antibody is a Rabbit Polyclonal against P2RY2.…
Ver producto